FAM83H Gene and Amelogenesis Imperfecta Type 3: Symptoms, Diagnosis and NGS Genetic Test Cost in India

Amelogenesis Imperfecta (AI) is a group of hereditary disorders that affect the formation and development of tooth enamel. It is characterized by the abnormal formation of the enamel, which can lead to discolored, weakened, and easily damaged teeth. The severity of the condition can vary from mild to severe, depending on the specific type of AI.

Amelogenesis Imperfecta Type 3 (AI-3) is caused by mutations in the FAM83H gene. This gene provides instructions for making a protein that is essential for the formation of tooth enamel. Mutations in the FAM83H gene can disrupt the normal development of tooth enamel, leading to the characteristic features of AI-3.

Symptoms of Amelogenesis Imperfecta Type 3

The symptoms of AI-3 can vary, but typically include:

• Discolored teeth that are either yellow, brown, or grey
• Teeth that are prone to chipping and breaking
• Teeth that are sensitive to hot and cold temperatures
• Teeth that are smaller than normal or have an abnormal shape
• Teeth that have an irregular surface texture

AI-3 is usually diagnosed during childhood, but symptoms may not become apparent until later in life. In some cases, individuals with AI-3 may also have other dental or skeletal abnormalities.

Diagnosis of Amelogenesis Imperfecta Type 3

Diagnosis of AI-3 typically involves a comprehensive dental exam, including X-rays and other imaging tests. A genetic test may also be recommended to confirm the presence of mutations in the FAM83H gene.

Genetic testing for AI-3 can be performed using Next-Generation Sequencing (NGS) technology. NGS is a powerful tool that allows for the rapid and accurate sequencing of DNA. This technology can identify mutations in the FAM83H gene with high sensitivity and specificity.

NGS Genetic Test Cost in India

The cost of NGS Genetic Testing for AI-3 in India can vary depending on the specific testing provider and the extent of the testing performed. However, on average, the cost of NGS Genetic Testing for AI-3 in India is around INR 20,000.

It is important to note that genetic testing for AI-3 is typically not covered by insurance, so individuals should be prepared to pay for the cost of testing out of pocket.

Conclusion

Amelogenesis Imperfecta Type 3 is a rare genetic disorder that can cause significant dental problems. Genetic testing using NGS technology can provide an accurate and reliable diagnosis of AI-3, allowing for appropriate treatment and management of the condition. While the cost of genetic testing can be significant, it is often necessary for individuals with AI-3 to receive a proper diagnosis and treatment plan.

 Note: We offer free home sample collection for online bookings for FAM83H Gene Amelogenesis imperfecta type 3 NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.