POLH Gene Xeroderma Pigmentosum, Variant Type NGS Genetic Test Cost INR:20000 Symptoms Diagnosis
Xeroderma pigmentosum (XP) is a rare genetic disorder that affects the skin and eyes. It is caused by a defect in the DNA repair system, which makes affected individuals extremely sensitive to sunlight. There are several different types of XP, one of which is caused by a variant in the POLH gene. In this blog, we will discuss this variant type of XP, the symptoms, diagnosis, and the cost of the NGS Genetic Test for it.
What is the POLH Gene?
POLH is a gene that provides instructions for making a protein called DNA polymerase eta. This protein is involved in the process of DNA replication and repair. When the DNA is damaged, the polymerase eta protein helps to repair it. However, if there is a variant in the POLH gene, the protein may not function properly, leading to a higher risk of developing skin cancer and other skin conditions.
What is Xeroderma Pigmentosum, Variant Type?
Xeroderma pigmentosum variant type is a rare subtype of XP that is caused by a variant in the POLH gene. This variant type of XP is less severe than other types of XP, but individuals with this condition are still at a higher risk of developing skin cancer and other skin conditions.
Symptoms of Xeroderma Pigmentosum, Variant Type
The symptoms of Xeroderma pigmentosum, variant type are similar to other types of XP and may include:
- Skin freckling
- Blistering and peeling of the skin after sun exposure
- Dry, rough, and scaly skin
- Development of small, rough, and scaly patches on the skin
- Premature aging of the skin
- Eye problems, such as photophobia, conjunctivitis, and clouding of the cornea
Diagnosis of Xeroderma Pigmentosum, Variant Type
Xeroderma pigmentosum, variant type is diagnosed through genetic testing. A small sample of blood or saliva is collected and analyzed for the presence of a variant in the POLH gene. If a variant is found, a diagnosis of XP variant type can be made.
NGS Genetic Test Cost for Xeroderma Pigmentosum, Variant Type
The cost of the NGS Genetic Test for Xeroderma pigmentosum, variant type in India is approximately INR 20,000. This test is performed by DNA Labs India, a leading genetics laboratory in the country. The test is non-invasive and involves the collection of a small sample of blood or saliva. The results of the test are available within a few weeks.
Conclusion
Xeroderma pigmentosum, variant type is a rare genetic disorder that is caused by a variant in the POLH gene. Individuals with this condition are at a higher risk of developing skin cancer and other skin conditions. The diagnosis of XP variant type is made through genetic testing, and the cost of the NGS Genetic Test for it is approximately INR 20,000 in India. If you suspect that you or a loved one may have XP variant type, it is important to seek medical attention and undergo genetic testing to confirm the diagnosis.
Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for POLH Gene Xeroderma pigmentosum, variant type NGS Genetic Test
| Test Name | POLH Gene Xeroderma pigmentosum, variant type NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | Dermatologist |
| Pre-test Information | Clinical History of Patient who is going for POLH Gene Xeroderma pigmentosum, variant type NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with POLH Gene Xeroderma pigmentosum, variant type NGS Genetic Test gene POLH |
| Disease | Osteology Dermatology Immunology Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for POLH Gene Xeroderma pigmentosum, variant type NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with POLH Gene Xeroderma pigmentosum, variant type NGS Genetic Test gene POLH |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for POLH Gene Xeroderma pigmentosum, variant type NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
