LAMC1 Gene and Dandy-Walker Malformation
DNA Labs India offers a Next Generation Sequencing (NGS) Genetic Test for the LAMC1 gene related to Dandy-Walker malformation and occipital cephaloceles. The cost of the test is INR 20,000. Read on to learn more about the LAMC1 gene and its relation to these conditions.
What is the LAMC1 Gene?
The LAMC1 gene encodes for laminin, a protein that is a major component of the extracellular matrix in many tissues. The extracellular matrix is a complex network of proteins and other molecules that provide structural support to cells and regulate cell behavior. Laminin is particularly important in the development and maintenance of the nervous system.
What is Dandy-Walker Malformation?
Dandy-Walker malformation is a rare congenital brain malformation that affects the cerebellum, the part of the brain that controls movement and coordination. In individuals with Dandy-Walker malformation, the cerebellum is abnormally small and may be partially or completely absent. The space where the cerebellum should be is instead filled with fluid. This can cause a range of symptoms, including developmental delay, problems with movement and coordination, and seizures.
What are Occipital Cephaloceles?
Occipital cephaloceles are another type of congenital brain malformation that involve a protrusion of brain tissue and membranes through a defect in the skull. This can cause a range of symptoms, depending on the size and location of the cephalocele.
How is LAMC1 Related to These Conditions?
Research has shown that mutations in the LAMC1 gene can cause Dandy-Walker malformation and occipital cephaloceles. These mutations are believed to disrupt the development and maintenance of the nervous system, particularly the cerebellum and the skull.
Symptoms of LAMC1-Related Conditions
The symptoms of LAMC1-related conditions can vary widely, but may include:
- Developmental delay
- Problems with movement and coordination
- Seizures
- Abnormalities in the shape or size of the skull
- Protrusions of brain tissue or membranes through the skull
Diagnosis of LAMC1-Related Conditions
Diagnosis of LAMC1-related conditions typically involves a combination of imaging studies, such as MRI or CT scans, and genetic testing. Genetic testing can confirm the presence of a mutation in the LAMC1 gene.
NGS Genetic Test for LAMC1 Gene
DNA Labs India offers a Next Generation Sequencing (NGS) Genetic Test for the LAMC1 gene related to Dandy-Walker malformation and occipital cephaloceles. This test can identify mutations in the LAMC1 gene that may be responsible for these conditions. The cost of the test is INR 20,000.
Conclusion
LAMC1-related conditions, such as Dandy-Walker malformation and occipital cephaloceles, can cause a range of symptoms and can be difficult to diagnose. However, genetic testing can be a valuable tool in identifying the underlying cause of these conditions. If you or a loved one are experiencing symptoms of these conditions, talk to your doctor about whether genetic testing may be appropriate.
Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for LAMC1 Gene Dandy-Walker malformation and occipital cephaloceles, LAMC1 related NGS Genetic Test
| Test Name | LAMC1 Gene Dandy-Walker malformation and occipital cephaloceles, LAMC1 related NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | Pediatrics |
| Pre-test Information | Clinical History of Patient who is going for LAMC1 Gene Dandy-Walker malformation and occipital cephaloceles, LAMC1 related NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with LAMC1 Gene Dandy-Walker malformation and occipital cephaloceles, LAMC1 related NGS Genetic Test gene LAMC1 |
| Disease | Dysmorphology |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for LAMC1 Gene Dandy-Walker malformation and occipital cephaloceles, LAMC1 related NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with LAMC1 Gene Dandy-Walker malformation and occipital cephaloceles, LAMC1 related NGS Genetic Test gene LAMC1 |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for LAMC1 Gene Dandy-Walker malformation and occipital cephaloceles, LAMC1 related NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
