MSH2 Gene Colorectal Cancer: Hereditary Nonpolyposis Type 1 NGS Genetic Test
Colorectal cancer is a common type of cancer that affects the colon and rectum. It is the third most commonly diagnosed cancer worldwide. Hereditary nonpolyposis colorectal cancer (HNPCC), also known as Lynch syndrome, is a hereditary condition that increases the risk of developing colorectal cancer. HNPCC accounts for 2-5% of all colorectal cancer cases.
HNPCC is caused by genetic mutations that affect the DNA repair system, which results in an increased risk of developing cancer. Mutations in the MSH2 gene are responsible for HNPCC type 1. The MSH2 gene provides instructions for making a protein that helps to repair damaged DNA. When this gene is mutated, the protein is not produced correctly, and the DNA repair system does not function properly. This increases the risk of developing cancer, especially colorectal cancer.
Symptoms of Colorectal Cancer
Colorectal cancer may not cause any symptoms in the early stages, but as the cancer grows, symptoms may include:
- Change in bowel habits, such as diarrhea or constipation
- Blood in the stool or rectal bleeding
- Abdominal pain or cramping
- Unexplained weight loss
- Fatigue or weakness
Diagnosis of Colorectal Cancer
Diagnosis of colorectal cancer involves a combination of physical examination, medical history, and diagnostic tests. The following tests may be used to diagnose colorectal cancer:
- Colonoscopy
- Fecal occult blood test
- CT scan
- MRI
NGS Genetic Test for MSH2 Gene Colorectal Cancer
NGS Genetic Testing is a type of genetic testing that can identify mutations in the MSH2 gene that cause HNPCC type 1. This test is done by analyzing a sample of blood or tissue. The cost of the NGS Genetic Test for MSH2 gene colorectal cancer in India is INR 20,000.
The NGS Genetic Test for MSH2 gene colorectal cancer is recommended for individuals with a family history of colorectal cancer or those who have been diagnosed with colorectal cancer at a young age. The test can identify individuals who are at increased risk of developing colorectal cancer due to a genetic mutation in the MSH2 gene. This information can be used to develop a personalized screening and surveillance plan to detect colorectal cancer at an early stage.
Conclusion
Colorectal cancer is a serious and potentially life-threatening condition. HNPCC type 1 is a hereditary condition that increases the risk of developing colorectal cancer. Mutations in the MSH2 gene are responsible for HNPCC type 1. The NGS Genetic Test for MSH2 gene colorectal cancer can identify individuals who are at increased risk of developing colorectal cancer due to a genetic mutation in the MSH2 gene. Early detection and treatment of colorectal cancer can improve outcomes and increase survival rates.
Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for MSH2 Gene Colorectal cancer, hereditary nonpolyposis type 1 NGS Genetic Test
| Test Name | MSH2 Gene Colorectal cancer, hereditary nonpolyposis type 1 NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | Oncologist |
| Pre-test Information | Clinical History of Patient who is going for MSH2 Gene Colorectal cancer, hereditary nonpolyposis type 1 NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with MSH2 Gene Colorectal cancer, hereditary nonpolyposis type 1 NGS Genetic Test gene MSH2 |
| Disease | Cancer |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for MSH2 Gene Colorectal cancer, hereditary nonpolyposis type 1 NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with MSH2 Gene Colorectal cancer, hereditary nonpolyposis type 1 NGS Genetic Test gene MSH2 |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for MSH2 Gene Colorectal cancer, hereditary nonpolyposis type 1 NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
