PALB2 Gene and its Link to Pancreatic Cancer Type 3: Understanding Susceptibility and NGS Genetic Testing
Pancreatic cancer is one of the deadliest forms of cancer, with a 5-year survival rate of only 10%. It is estimated that in 2021, around 60,430 people in the United States will be diagnosed with pancreatic cancer and around 48,220 people will die from it. One of the genes that have been linked to pancreatic cancer is the PALB2 gene.
What is the PALB2 Gene?
The PALB2 gene, also known as Partner and Localizer of BRCA2, is a tumor suppressor gene that helps repair damaged DNA. It works with the BRCA2 gene to repair double-stranded DNA breaks. Mutations in the PALB2 gene can increase the risk of developing certain types of cancer, including breast, ovarian, and pancreatic cancer.
Link between PALB2 Gene and Pancreatic Cancer Type 3
Pancreatic cancer is classified into three types: pancreatic cancer type 1, pancreatic cancer type 2, and pancreatic cancer type 3. Pancreatic cancer type 3, also known as ductal adenocarcinoma, is the most common type of pancreatic cancer, accounting for around 90% of cases. Studies have shown that mutations in the PALB2 gene can increase the risk of developing pancreatic cancer type 3.
Symptoms and Diagnosis of Pancreatic Cancer Type 3
Early stages of pancreatic cancer type 3 may not show any symptoms. However, as the cancer grows, the following symptoms may appear:
- Pain in the upper abdomen or back
- Loss of appetite
- Weight loss
- Fatigue
- Jaundice (yellowing of the skin and eyes)
Diagnosis of pancreatic cancer type 3 involves several tests, including:
- Physical exam
- Imaging tests (CT scan, MRI, ultrasound)
- Biopsy
NGS Genetic Test for PALB2 Gene Mutation
NGS (Next Generation Sequencing) Genetic Test is a powerful tool that helps detect mutations in the PALB2 gene. The test involves analyzing a person’s DNA to identify any changes in the PALB2 gene that may increase the risk of developing pancreatic cancer type 3.
Cost of NGS Genetic Test for PALB2 Gene Mutation
The cost of the NGS Genetic Test for PALB2 Gene Mutation varies depending on the laboratory and the country. In India, the cost of the test ranges from INR 20,000 to INR 30,000.
Conclusion
The PALB2 gene has been linked to pancreatic cancer type 3, and mutations in this gene can increase the risk of developing the disease. It is important to be aware of the symptoms of pancreatic cancer type 3 and get diagnosed early. NGS Genetic Test for PALB2 Gene Mutation is a useful tool that can help identify the risk of developing pancreatic cancer type 3. If you have a family history of pancreatic cancer or have any of the symptoms mentioned above, it is recommended to consult a doctor and get tested.
At DNA Labs India, we offer reliable and accurate NGS Genetic Testing for PALB2 Gene Mutation at an affordable cost. Contact us today to learn more about our testing services.
| Test Name | PALB2 Gene Pancreatic cancer type 3, susceptibility to NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | Oncologist |
| Pre-test Information | Clinical History of Patient who is going for PALB2 Gene Pancreatic cancer type 3, susceptibility to NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with PALB2 Gene Pancreatic cancer type 3, susceptibility to NGS Genetic Test gene PALB2 |
| Disease | Cancer |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for PALB2 Gene Pancreatic cancer type 3, susceptibility to NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with PALB2 Gene Pancreatic cancer type 3, susceptibility to NGS Genetic Test gene PALB2 |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for PALB2 Gene Pancreatic cancer type 3, susceptibility to NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
