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MGMT Methylation Panel Cost

Original price was: ₹80,000.Current price is: ₹60,000.

-25%

The Methylation Panel Test by DNA Labs India provides valuable information about the biochemical methylation pathway. This test reveals essential insights into a patient’s nutritional needs, including amino acids, vitamins, and minerals, by measuring methylation metabolites and genetic single nucleotide polymorphisms (SNPs).

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MGMT Methylation Test Price 60000 INR

DNA Methylation Test

  • MGMT Gene: The O6-methylguanine-DNA methyltransferase (MGMT) is a gene responsible for DNA repair. It plays a crucial role in mending specific DNA damage in normal cells.
  • Methylation: Methylation is a cellular process that can deactivate genes. In the case of glioblastoma, methylation can affect the MGMT gene, leading to its inactivation.

Elements of the MGMT Methylation Panel:

The MGMT methylation panel typically examines:

  • MGMT Promoter Methylation: This is the principal element, determining if methylation has silenced the MGMT gene.

Information Before the Test:

  • Who it’s for: This test is mainly for individuals who have been diagnosed with glioblastoma.
  • Advantages: Understanding the MGMT methylation status allows physicians to customize treatment strategies.

Details of the Test:

  • Sample: Typically, a tissue or Blood sample from the tumor is used.
  • Procedure: The sample is subjected to a lab analysis to identify MGMT gene methylation.
  • Turnaround Time: Usually, results are ready within a span of 15 to 20 business days.

Significance of MGMT Methylation Testing:

  • Treatment Choices: Patients with MGMT methylation tend to have a better response to certain chemotherapy drugs, such as temozolomide.
  • Individualized Approach: The test results can assist doctors in personalizing treatment plans, maximizing efficacy and reducing side effects.

Further Points to Consider:

  • While MGMT methylation testing is a useful tool, it’s not the only factor influencing treatment decisions. Other aspects like overall health and tumor characteristics are also considered.
  • Currently, this test is not provided by DNA Labs India.

Taking Charge of Your Health:

MGMT methylation testing provides crucial information for glioblastoma therapy. Discussing this testing option with your physician can enable you to take a proactive role in your healthcare journey.

The Methylation Panel is an advanced test designed to offer valuable insights into the crucial biochemical methylation pathway. It measures methylation metabolites in plasma and analyzes genetic single nucleotide polymorphisms (SNPs) using a buccal swab. Patient results are presented in an easy-to-understand Interpretation-at-a-Glance (IAAG) graphic on the front page for a quick assessment of methylation status. Additionally, the report includes a visual representation of the methylation pathway, aiding in a clear understanding of the involved biochemistry.

Promoting Personalized Wellness in Aging

The Methylation Panel represents an innovative testing method aimed at providing insights into the pivotal biochemical methylation pathway. This involves measuring methylation metabolites within plasma and analyzing genetic single nucleotide polymorphisms (SNPs) through buccal swabs. The resulting patient outcomes are summarized in an easy-to-read Interpretation-at-a-Glance (IAAG) graphic on the front page, allowing for swift evaluation of methylation status. Additionally, the comprehensive report includes a visual representation of the methylation pathway, enhancing comprehension of the underlying biochemistry.



Understanding Methylation Methylation, a chemical process occurring billions of times per second in every cell of the body, involves the transfer and donation of methyl groups among various molecules, altering their structure and function. These methyl groups serve as countless switches that regulate gene activity, aid in mood regulation, detoxify hormones, facilitate energy production, and support healthy aging.

For this process to function optimally, essential vitamins, minerals, and amino acids from the diet are crucial. Genetic elements and oxidative stressors also play roles in influencing the efficiency of this pathway.

Significance of Methylation

Methylation plays a vital role in DNA and RNA creation, gene expression regulation, creatine production essential for skeletal muscle function, fundamental energy generation, fat metabolism, immune system responses, vascular health, and cell membrane repair. Additionally, it actively participates in neurotransmitter production and metabolism, contributing to mood regulation, while also aiding in the neutralization of toxins and hormones.

Which Patients Benefit from the Methylation Panel?

Given its comprehensive impact on fundamental human physiology, methylation defects can manifest across a wide spectrum of symptoms. The Methylation Panel proves beneficial for patients experiencing:

  • Uncertain detoxification (including those undergoing hormone therapy, alcohol consumers, or exposed to toxins)3,4,5
  • Elevated cancer risk6,7,8,9
  • Cardiovascular ailments (non-coronary atherosclerosis, hypertension, coronary artery disease)10,11,12,13
  • Psychiatric and mood disorders (schizophrenia, autism, bipolar disorder, anxiety, depression)6,14,15,16,17
  • Neurological conditions (Parkinson’s disease, cognitive decline)18,19,20
  • Chronic fatigue21

How Methylation Panel Results Help

The Methylation Panel’s outcomes highlight nutritional requirements such as amino acids, vitamins, and minerals. This knowledge aids in tailoring dietary and nutraceutical treatments. Furthermore, understanding genetic predispositions can assist in targeting supplementation to counter potential methylation deficiencies.

Symptoms of MGMT Methylation

MGMT Methylation is not a disease, but a biological marker that indicates the level of MGMT methylation in a patient’s DNA. However, MGMT Methylation is associated with certain types of cancer, including:

  • Glioblastoma (brain cancer)
  • Colorectal cancer
  • Lung cancer
  • Breast cancer

The symptoms of these cancers may include:

  • Headaches
  • Seizures
  • Nausea and vomiting
  • Bowel changes
  • Chest pain
  • Breast lumps

It is important to note that these symptoms may also be caused by other conditions, and a proper diagnosis is necessary.

Diagnosis of MGMT Methylation

MGMT Methylation can be diagnosed through a DNA test, such as the MGMT Methylation Assay. This test is usually conducted on a tissue sample from the cancerous area, which is obtained through biopsy or surgery.

Once the tissue sample is obtained, it is sent to a laboratory for analysis. The MGMT Methylation Assay determines the level of MGMT methylation in the DNA and provides valuable information for cancer treatment.

Conclusion

MGMT Methylation Assay is a valuable tool in cancer treatment, as it provides information about the level of MGMT methylation in a patient’s DNA. This information can help doctors determine the most effective treatment for the patient. If you are experiencing symptoms of cancer, it is important to consult a doctor for proper diagnosis and treatment.

For more information about MGMT Methylation Assay, contact DNA Labs India.

Test NameMGMT Methylation Panel
Sample typeBlood”,”Tissue
Test typeGenetic
Pre-test InformationThe Methylation Panel stands as a groundbreaking test crafted to provide understanding of the pivotal biochemical methylation pathway. Plasma measurement of methylation metabolites and the analysis of genetic single nucleotide polymorphisms (SNPs) via buccal swab form the core of this assessment. Patient outcomes are summarized on a user-friendly Interpretation-at-a-Glance (IAAG) graphic on the front page for swift evaluation of methylation status. Furthermore, the report includes a methylation pathway graphic to offer a lucid comprehension of the underlying biochemistry.
DiseaseGenetics
MethodMLPA
PurposeThe Methylation Panel from DNA Labs India integrates both phenotypic and genotypic data into a single profile. It simplifies intricate biochemistry using easily understandable graphics. This comprehensive assessment covers methylation and transsulfuration markers, along with numerous genetic SNPs, offering a thorough evaluation unparalleled in methylation assessment.
PreparationAmbient
FastingThe Methylation Panel stands as a groundbreaking test crafted to provide understanding of the pivotal biochemical methylation pathway. Plasma measurement of methylation metabolites and the analysis of genetic single nucleotide polymorphisms (SNPs) via buccal swab form the core of this assessment. Patient outcomes are summarized on a user-friendly Interpretation-at-a-Glance (IAAG) graphic on the front page for swift evaluation of methylation status. Furthermore, the report includes a methylation pathway graphic to offer a lucid comprehension of the underlying biochemistry.
Get Reports15-20 days
Test Price ₹ 60000 INR

 Note: We offer free home sample collection for online bookings for MGMT Methylation Panel and the test costs special discounted price of 60000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.