Overview
Hi-C sequencing is a cutting-edge molecular technique that allows researchers and clinicians to study the three-dimensional organization of the genome. By cross-linking chromatin, digesting DNA, and ligating fragments, Hi-C sequencing identifies chromatin interactions and spatial relationships between genomic regions. This method is invaluable for diagnosing genetic disorders, as it can detect chromosomal rearrangements, copy number variations, and mutations in non-coding regions that may be missed by traditional sequencing. At DNA Labs India, we offer Hi-C sequencing at an affordable cost of INR 135,000, with free home sample collection across numerous cities in India. The test is particularly useful for individuals with symptoms such as developmental delays, intellectual disability, autism spectrum disorders, and other congenital anomalies. With a turnaround time of 6 weeks, our comprehensive report provides detailed insights into the genomic structure, aiding in accurate diagnosis and personalized treatment planning. This technique is a powerful tool for medical research and clinical diagnostics, offering a comprehensive view of the genome that supports advanced genetic analysis.
To be completed — reclassified from Tests on 2026-11-13.
The purpose of Hi-C sequencing is to map the three-dimensional structure of the genome, identify chromatin interactions, and detect genetic mutations that contribute to various disorders. It helps in understanding the functional organization of the genome and diagnosing conditions linked to structural variations, such as chromosomal rearrangements and copy number variations.
Sample requirements
What to send us
Deliverables & turnaround
What you receive
Turnaround: 6 weeks
Pricing
Transparent pricing
| Option | Turnaround | Price (INR) | Unit |
|---|---|---|---|
| Standard | 6 weeks | ₹135,000 | per sample |
Limitations & precautions
What this service cannot do
Questions customers ask
Frequently asked questions
What is Hi-C sequencing?
Hi-C sequencing is a molecular technique used to study the three-dimensional structure of the genome by identifying chromatin interactions and spatial relationships between DNA regions.
How much does Hi-C sequencing cost in India?
At DNA Labs India, Hi-C sequencing costs INR 135,000, which includes home sample collection and report generation.
What are the indications for Hi-C sequencing?
Indications include developmental delays, intellectual disability, autism spectrum disorders, multiple congenital anomalies, unexplained growth retardation, recurrent infections, and seizures.
How is Hi-C sequencing performed?
The process involves cross-linking chromatin, digesting DNA, ligating fragments, and sequencing to map chromatin interactions and genomic structure.
What is the turnaround time for results?
Results are typically available within 6 weeks after sample collection.
Is home sample collection available for Hi-C sequencing?
Yes, DNA Labs India offers free home sample collection for online bookings across numerous cities in India.
What are the benefits of Hi-C sequencing?
Benefits include identifying chromatin interactions, studying 3D genome structure, detecting mutations in non-coding regions, and providing a comprehensive view of the genome for diagnosis.
Are there any risks associated with Hi-C sequencing?
Risks are minimal, primarily related to sample collection, such as bruising from blood draw. The sequencing process itself poses no significant risks.
How should I prepare for the Hi-C sequencing test?
No specific preparation is required. Inform the lab of any medications or medical conditions before sample collection.
What do the results of Hi-C sequencing mean?
Results provide a map of chromatin interactions and genomic structure, which can help diagnose genetic disorders. Interpretation should be done by a qualified geneticist.
Is Hi-C sequencing covered by insurance?
Coverage depends on your insurance policy. It is not typically covered under government schemes like PMJAY or CGHS; check with your provider for details.
How can I book a Hi-C sequencing test?
You can book online through DNA Labs India's website or contact their team directly for assistance with sample collection and testing.
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