Overview
Mitochondrial genome sequencing is a comprehensive genetic test that analyzes the complete mitochondrial DNA (mtDNA) sequence. The mitochondria are cellular organelles responsible for energy production, and mutations in mtDNA can lead to a wide range of clinical conditions, including mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS), myoclonic epilepsy with ragged red fibers (MERRF), and Leber hereditary optic neuropathy (LHON). At DNA Labs India, we utilize advanced next-generation sequencing technology and sophisticated bioinformatics pipelines to detect pathogenic variants, deletions, and heteroplasmy levels. The test is performed on extracted DNA from blood or saliva samples, ensuring high accuracy. Our expert geneticists and bioinformaticians interpret the results in the context of your symptoms and family history, providing actionable insights for diagnosis and management. With a turnaround time of 4 weeks and a cost of INR 20000, we make advanced genetic testing accessible across India. Free home sample collection is available in over 200 cities, ensuring convenience and reliability.
To be completed — reclassified from Tests on 2026-11-13.
The purpose of mitochondrial genome sequencing data analysis is to identify genetic variations in the mitochondrial DNA that may be responsible for unexplained neurological, muscular, or metabolic symptoms. This test aids in confirming a clinical diagnosis of mitochondrial disease, guiding treatment decisions, assessing recurrence risks, and enabling family planning. It is particularly useful when other diagnostic tests have been inconclusive.
Sample requirements
What to send us
Deliverables & turnaround
What you receive
Turnaround: Results are typically delivered within 4 weeks after the sample reaches the laboratory.
Pricing
Transparent pricing
| Option | Turnaround | Price (INR) | Unit |
|---|---|---|---|
| Standard | Results are typically delivered within 4... | ₹20,000 | per sample |
Limitations & precautions
What this service cannot do
Questions customers ask
Frequently asked questions
What is mitochondrial genome sequencing?
Mitochondrial genome sequencing is a test that analyzes the complete DNA sequence of the mitochondria, the energy-producing structures in cells. It helps identify mutations that may cause various genetic disorders.
Who should consider this test?
Individuals with symptoms like unexplained fatigue, muscle weakness, seizures, or vision/hearing problems, or those with a family history of mitochondrial disease, may benefit from this test.
What sample is required?
The test requires extracted DNA, which is typically obtained from a blood or saliva sample. Our team will guide you on the collection process.
How long does it take to get results?
Results are usually available within 4 weeks after the sample is received at the laboratory.
Is fasting required before the test?
No, fasting is not required for this test. You can eat and drink normally before sample collection.
What does the test cost?
The cost of mitochondrial genome sequencing data analysis at DNA Labs India is INR 20000, which includes home sample collection and a comprehensive report.
Can this test detect all mitochondrial disorders?
This test detects mutations in the mitochondrial DNA. However, some mitochondrial disorders are caused by nuclear gene mutations, which are not covered by this test.
What is heteroplasmy?
Heteroplasmy refers to the presence of both normal and mutated mitochondrial DNA in a cell. The test reports the percentage of mutated DNA, which can influence symptom severity.
Will I need genetic counseling?
Yes, genetic counseling is recommended before and after the test to understand the implications of the results, especially if a pathogenic variant is found.
Is home sample collection available?
Yes, we offer free home sample collection for this test across many cities in India. Please check availability in your area.
Are there any risks associated with the test?
The test is safe with minimal risks, such as slight bruising at the blood draw site. There are no significant physical risks.
How accurate is the test?
The test is highly accurate, using next-generation sequencing technology. However, low-level heteroplasmy may not be detected, and variants of uncertain significance may be reported.
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