Short Description

5-Fluorouracil (5-FU) is a commonly used anticancer drug. It functions by irreversibly inhibiting thymidylate synthase. 5-FU is widely used in a number of cancers worldwide. Detoxification of 5-FU is mediated by the dihydropyrimidine dehydrogenase (DPD) gene . Apart from 5-FU, the gene also is involved in detoxification of Capecitabine, and Tegafur. Genetic variations in the gene can cause a partial or complete deficiency of function, which may lead to severe drug toxicity.

PreTest Information

Duly filled Genomics clinical Information Requisition Form (Form 20) is mandatory.

Detail Description

5 FLUOROURACIL (5FU) TOXICITY Test: Symptoms, Diagnosis and Cost in India

5 Fluorouracil (5FU) is a chemotherapy drug used in the treatment of various cancers such as breast, colon, and stomach. However, the drug is known to have toxic effects on the body, leading to 5FU toxicity. The toxicity can cause severe side effects, including nausea, vomiting, diarrhea, and even death. Therefore, it is essential to diagnose and treat 5FU toxicity early on. In this blog, we will discuss the symptoms, diagnosis, and cost of 5FU toxicity test in India.

Symptoms of 5FU Toxicity

The symptoms of 5FU toxicity can vary depending on the severity of the condition. The common symptoms include:

• Nausea and vomiting
• Diarrhea
• Fever
• Mouth sores
• Loss of appetite
• Abdominal pain
• Fatigue
• Low blood cell counts
• Hand-foot syndrome (redness, swelling, and pain in the hands and feet)

If you are experiencing any of these symptoms while undergoing 5FU chemotherapy treatment, it is essential to inform your doctor immediately.

Diagnosis of 5FU Toxicity

The diagnosis of 5FU toxicity involves a series of tests to determine the level of toxicity in the body. The tests include:

• Blood tests: The blood test will check the levels of white blood cells, red blood cells, and platelets in the body.
• Liver function tests: The liver function test will check the level of liver enzymes in the body.
• Kidney function tests: The kidney function test will check the level of creatinine in the body.
• Electrolyte tests: The electrolyte test will check the level of sodium, potassium, and calcium in the body.
• Urine test: The urine test will check for the presence of blood or protein in the urine.

The doctor may also perform a physical examination to determine the severity of the symptoms and recommend a course of treatment accordingly.

Cost of 5FU Toxicity Test in India

The cost of 5FU toxicity test can vary depending on the hospital or diagnostic center. However, on average, the test can cost around INR 10,000 in India.

It is essential to note that the cost of treatment for 5FU toxicity can be significantly higher than the cost of the test. Therefore, it is essential to get the test done at the earliest to prevent severe complications.

Conclusion

5FU toxicity is a severe condition that requires immediate medical attention. It is essential to be aware of the symptoms and seek medical help if you experience any of them while undergoing chemotherapy treatment. The 5FU toxicity test is an effective way to diagnose the condition and prevent severe complications. The cost of the test is affordable in India, and it is recommended to get the test done at the earliest to ensure timely treatment.

At DNA Labs India, we offer reliable and accurate 5FU toxicity test services. Our team of experienced professionals ensures timely and accurate diagnosis of the condition. Contact us today to know more about our services.