Understanding ATXN10 Gene and Spinocerebellar Ataxia Type 10
Spinocerebellar ataxia type 10 (SCA10) is a rare, inherited neurological disorder that affects the cerebellum and brainstem. The disease is caused by a mutation in the ATXN10 gene, which provides instructions for making a protein that is essential for normal brain function.
SCA10 is an autosomal dominant disorder, which means that a person only needs to inherit one copy of the mutated gene from either parent to develop the disease. The age of onset for SCA10 can vary, but typically symptoms appear in midlife, around age 40 or 50.
Symptoms of SCA10
The symptoms of SCA10 can vary from person to person, but common signs of the disease include:
- Problems with coordination and balance
- Difficulty walking or standing
- Slurred speech or difficulty swallowing
- Vision problems
- Tremors or shaking
- Muscle stiffness or rigidity
- Difficulty with fine motor skills, such as writing or buttoning clothes
Diagnosing SCA10
Diagnosing SCA10 requires a thorough evaluation by a medical professional, including a neurological exam and genetic testing. The genetic test for SCA10 involves analyzing a sample of a person’s DNA to look for mutations in the ATXN10 gene.
Currently, there is no cure for SCA10, but treatment options are available to manage the symptoms of the disease. These may include physical therapy, speech therapy, and medication to alleviate tremors or other movement problems.
NGS Genetic Test Cost for SCA10
The cost of a Next Generation Sequencing (NGS) Genetic Test for SCA10 in India is approximately INR 20,000. This test is designed to detect mutations in the ATXN10 gene that are associated with SCA10. The test can be performed on a blood or saliva sample, and results are typically available within a few weeks.
Conclusion
SCA10 is a rare, inherited neurological disorder that can cause a range of symptoms, including problems with coordination and balance, difficulty speaking or swallowing, and tremors or shaking. Genetic testing is available to diagnose SCA10 and can help individuals and families better understand their risk for developing the disease. If you or a loved one are experiencing symptoms of SCA10, it is important to seek medical attention and discuss treatment options with a healthcare professional.
| Test Name | ATXN10 Gene Spinocerebellar ataxia type 10, autosomal dominant NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card o |
| Test type | Neurologist |
| Pre-test Information | Clinical History of Patient who is going for ATXN10 Gene Spinocerebellar ataxia type 10, autosomal dominant NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with ATXN10 Gene Spinocerebellar ataxia type 10, autosomal dominant |
| Disease | Neurological Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for ATXN10 Gene Spinocerebellar ataxia type 10, autosomal dominant NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with ATXN10 Gene Spinocerebellar ataxia type 10, autosomal dominant |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for ATXN10 Gene Spinocerebellar ataxia type 10, autosomal dominant NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
