Breast Cancer BRCA1 BRCA2 Gene Test

Breast Cancer BRCA1 BRCA2 Gene Test

Disease: Cancer

Method: NGS Technology

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Sample Types
  • Blood EDTA Tube

15,000.00/- Rs ₹28,000.0046% off

  • Results in : 3 to 4 Weeks

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Breast Cancer BRCA1 BRCA2 Gene Test Cost 15000 Rs


Test type Oncologist
Pre-test Information Clinical History of Patient who is going for Breast Cancer BRCA Panel NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with BRCA1, BRCA2
Report Delivery 3 to 4 Weeks
Components
Price ₹ 15000
Method NGS Technology

Breast Cancer BRCA1 BRCA2 Gene Test Details


Short Description

List of genes tested using NGS technology for detection of variant and mutation in Breast Cancer BRCA Panel are BRCA1, BRCA2

Test Specifications

  • Speciality: Oncologist

  • Components:

  • Department: Genetics

  • Shipping Stability: Ambient Room Temperature

PreTest Information

Clinical History of Patient who is going for Breast Cancer BRCA Panel NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with BRCA1, BRCA2

Detail Description

What is a BRCA genetic test?

A BRCA test looks for changes, known as mutations, in genes called BRCA1 and BRCA2. Genes are parts of DNA passed down from your mother and father. They carry information that determines your unique traits, such as height and eye colour. They are also responsible for certain health conditions. BRCA1 and BRCA2 are genes that protect cells by making proteins that help prevent tumours from forming. 

A mutation in BRCA1 or BRCA2 can cause cell damage that may lead to cancer. Women with a mutated BRCA have a higher risk of getting breast-ovarian cancer. Men with a mutated BRCA are at a higher risk of getting breast prostate cancer. Not everyone who inherits a BRCA1 or BRCA2 mutation will get cancer. Other factors, including your lifestyle and environment, can affect your cancer risk. 

What is it used for?

This test is used to find out if you have BRCA1 or BRCA2 mutation. A BRCA mutation can increase your risk of getting cancer. 

Why do I need a BRCA test?

BRCA testing is not recommended for most people. BRCA mutations are rare, affecting only about 0.2 per cent of the U.S. population. But you may want this test if you think you are at a higher risk of having the mutation. You are more likely to have a BRCA mutation if you: 

  • Have or had breast cancer in both breasts
  • Have or had both breast and ovarian cancer
  • Have one or more family members with breast cancer
  • Have a male relative with breast cancer
  • Have a relative already diagnosed with a BRCA mutation

What is the cost of the BRCA Test?

BRCA Test costs 15000 Rs at DNA Labs India.

What is the reporting time for BRCA Test?

For reports, it will take 3-4weeks

What happens during a BRCA test?

A health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes.

Are there any risks to the test?

There is very little risk to having a blood test. You may have slight pain or bruise at the spot where the needle was put in, but most symptoms go away quickly. 

What is Hereditary Breast and Ovarian Cancer?

A diagnosis of Hereditary Breast and Ovarian Cancer Syndrome (HBOC) is considered when there are multiple cases of breast cancer ovarian cancer on the same side of the family. The chance that a family has HBOC increases in any of these situations: 

  • 1 or more women are diagnosed at age 45 or younger 1 or more women are diagnosed with breast cancer before age 50 with an additional family history of cancer, such as prostate cancer melanoma pancreatic cancer
  • There are breast and ovarian cancers in multiple generations on the same side of the family, such as having both a grandmother and an aunt on the father's side both diagnosed with these cancers.

How is HBOC inherited?

Normally, each person has 2 copies of each gene in their body's cells: 1 copy is inherited from a person's mother and 1 copy is inherited from a person's father. HBOC follows an autosomal dominant inheritance pattern. This means that a mutation needs to happen in only 1 copy of the gene for the person to have an increased risk of getting that disease.

This means that a parent with a mutation may pass along a copy of the gene with the mutation. Therefore, a child who has a parent with a mutation has a 50% chance of inheriting that mutation. A sibling or parent of a person who has a mutation also has a 50% chance of having inherited the same mutation. However, if the parents test negative for the mutation (meaning each person's test results found no mutation), the risk to the siblings significantly decreases but their risk may still be higher than the average risk.

Genetic Testing for Hereditary Breast and Ovarian Cancer

Genetic testing is available for hereditary breast and ovarian cancer. Most breast and ovarian cancer is not caused by inherited mutations, so this testing will not help most women with a family health history of breast and ovarian cancer. The testing will not identify the cause for some hereditary breast and ovarian cancers. Testing for hereditary breast and ovarian cancer looks for mutations in the BRCA1 and BRCA2 that looks for mutations in several genes at the same time, including BRCA1 and BRCA2.

How Do I Interpret the Test Results?

A negative test result means that a breast cancer mutation was not identified. If another testing has identified a mutation in your family, a negative test means you do not have the specific mutation. Therefore, your risk of cancer is the same as someone in the general population who has a family history of breast cancer.

If a BRCA1 or BRCA2 mutation has not been previously found in your family, a negative result should be interpreted cautiously. There is still a chance that you may be at higher risk for breast cancer because of changes in genes other than those that doctors can test for. A positive test result means that a mutation known to raise the risk of breast and ovarian cancer was identified.

Frequently Asked Questions

  • What is the cost of Breast Cancer BRCA1 BRCA2 Gene Test?

    Cost of Breast Cancer BRCA1 BRCA2 Gene Test is 15000 Rs

    Breast Cancer BRCA1 BRCA2 Gene Test Price in India ₹ 15000
  • What is a BRCA genetic test?

    A BRCA genetic test looks for changes, known as mutations, in genes called BRCA1 and BRCA2. Genes are parts of DNA passed down from your mother and father. They carry information that determines your unique traits, such as height and eye colour.

  • Why do I need a BRCA genetic test?

    BRCA testing is not recommended for most people. BRCA gene mutations are rare. But you may want this test if you think you are at a higher risk of having the mutation. You are more likely to have a BRCA mutation if you:

    Have or had breast cancer that was diagnosed before age 50

    Have or had breast cancer in both breasts.

    Have or had both breast and ovarian cancer 

  • What do the results mean?

    A negative result means no BRCA gene mutation was found, but it doesn't mean you won't ever get cancer. An uncertain result means some kind of BRCA gene mutation was found, but it may or may not be linked with increased cancer risk. A positive result means a mutation in BRCA1 or BRCA2 was found. These mutations put you at a higher risk of getting cancer. But not everyone with the mutation gets cancer. 

  • Who should consider BRCA gene testing?

    You might be at increased risk of having an inherited gene mutation that increases the risk of breast and ovarian cancers and a candidate for genetic testing if you have:

    A personal history of breast cancer diagnosed before age 45 

    A personal history of breast cancer diagnosed before age 50 and second primary breast cancer, one or more relatives with breast cancer, or an unknown or limited family medical history 

    A personal history of triple-negative breast cancer diagnosed at age 60 or younger

  • What happens during a BRCA genetic test?

    A health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes. 

  • Are there any risks to the test?

    There is very little risk to having a blood test. You may have slight pain or bruise at the spot where the needle was put in, but most symptoms go away quickly. 

  • What is the cost of the BRCA Test?

    The cost of the BRCA Test is 20000 Rs

  • How many days does it take for reports?

    Reports take 4-5 weeks

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