DLL4 Gene Adams-Oliver Syndrome Type 6 NGS Genetic Test Cost INR:20000 Symptoms Diagnosis
Adams-Oliver Syndrome (AOS) is a rare genetic disorder that affects the development of the limbs, scalp, and skull. AOS is caused by mutations in several genes, including DLL4. DLL4 Gene Adams-Oliver Syndrome Type 6 is caused by mutations in the DLL4 gene and is inherited in an autosomal dominant pattern.
The DLL4 gene provides instructions for making a protein called delta-like 4 (DLL4). This protein is involved in the development and maintenance of blood vessels. Mutations in the DLL4 gene lead to the production of a nonfunctional DLL4 protein, which can cause abnormalities in blood vessel development and lead to the symptoms of AOS.
NGS Genetic Test for DLL4 Gene Adams-Oliver Syndrome Type 6 is available at DNA Labs India. The cost of the test is INR:20000. The test can help diagnose the condition and identify mutations in the DLL4 gene that may be causing the symptoms.
Symptoms of DLL4 Gene Adams-Oliver Syndrome Type 6
- Missing or underdeveloped fingers or toes
- Scalp defects, such as missing skin or hair
- Abnormalities in the skull, such as missing bones or fused bones
- Heart defects
- Developmental delay or intellectual disability
Diagnosis of DLL4 Gene Adams-Oliver Syndrome Type 6
A diagnosis of AOS is typically made based on the presence of characteristic symptoms. Genetic testing can confirm the diagnosis and identify the specific gene mutation causing the condition. NGS Genetic Test for DLL4 Gene Adams-Oliver Syndrome Type 6 is a highly accurate and reliable test for diagnosing the condition.
If you or someone you know is experiencing symptoms of DLL4 Gene Adams-Oliver Syndrome Type 6, contact DNA Labs India to schedule a test. Our team of experts can provide you with the information and support you need to manage the condition and improve your quality of life.
Adams-Oliver syndrome (AOS) is a rare genetic disorder that primarily affects the skin, fingers, and toes. It is characterized by a combination of abnormalities, including congenital absence of skin (aplasia cutis congenita) and malformations of the fingers and/or toes. Adams-Oliver syndrome is caused by mutations in various genes, one of which is the DLL4 gene.
The DLL4 gene encodes a protein that is involved in the Notch signaling pathway, which plays a critical role in the development of various tissues and organs during embryonic growth. Mutations in the DLL4 gene can disrupt the normal development of the skin, blood vessels, and other structures, leading to the features seen in Adams-Oliver syndrome.
An NGS (Next-Generation Sequencing) Genetic Test can analyze the DLL4 gene for mutations that are known to be associated with Adams-Oliver syndrome type 6. Identifying these mutations can help with the diagnosis and management of the condition.
Individuals with Adams-Oliver syndrome may present with scalp defects (aplasia cutis congenita) and malformations of the fingers and toes. Other features, such as heart defects and vascular anomalies, can also occur.
If you suspect that you or someone you know might have Adams-Oliver syndrome type 6 or if there is a family history of the condition, consulting with a medical geneticist or a genetic counselor is advisable. They can guide you through the process of genetic testing, explain the implications of the results, and provide information about the condition, management, and support resources. Keep in mind that genetic testing results are best interpreted in consultation with qualified healthcare professionals.
| Test Name | DLL4 Gene Adams-Oliver syndrome type 6 NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | Pediatrics |
| Pre-test Information | Clinical History of Patient who is going for DLL4 Gene Adams-Oliver syndrome type 6 NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with DLL4 Gene Adams-Oliver syndrome type 6 NGS Genetic Test gene DLL4 |
| Disease | Dysmorphology |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for DLL4 Gene Adams-Oliver syndrome type 6 NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with DLL4 Gene Adams-Oliver syndrome type 6 NGS Genetic Test gene DLL4 |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for DLL4 Gene Adams-Oliver syndrome type 6 NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
