DPD GENE MUTATIONS (5-FU TOXICITY) DETECTION Test

DPD GENE MUTATIONS (5-FU TOXICITY) DETECTION Test

Disease: Pharmacogenomics

Method: PCR

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Sample Types
  • 4 mL (2 mL min.) whole blood in 1 Lavender top (EDTA) tube. Ship refrigerated. DO NOT FREEZE. Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.

9,828.00/- Rs ₹10,920.0010% off

  • Results in : 12-15 working days

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DPD GENE MUTATIONS (5-FU TOXICITY) DETECTION Test Cost 9828 Rs


Test Name DPD GENE MUTATIONS (5-FU TOXICITY) DETECTION Test
Test type Physician
Pre-test Information Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.
Report Delivery 12-15 working days
Components
Price ₹ 9828
Method PCR

DPD GENE MUTATIONS (5-FU TOXICITY) DETECTION Test Details


Short Description

Dihydropyrimidine dehydrogenase (DPD) enzyme is responsible for the detoxifying metabolism of fluoropyrimidines, a class of drugs that includes 5-Fluorouracil, Capecitabine, and Tegafur. Genetic variations within the DPD gene can lead to reduced or absent DPD activity, and individuals who are heterozygous or homozygous for these variations may have partial or complete DPD deficiency an estimated 0.2% of individuals have complete DPD deficiency. Those with partial or complete DPD deficiency have a significantly increased risk of severe or even fatal drug toxicities when treated with fluoropyrimidines examples of toxicities include myelosuppression, neurotoxicity and hand-foot syndrome.

Test Specifications

  • Speciality: Physician

  • Components:

  • Department: MOLECULAR DIAGNOSTICS

  • Shipping Stability: Room Temperature: NA, Refrigerator:1 week, Frozen: NA

PreTest Information

Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.

Detail Description

Dihydropyrimidine dehydrogenase (DPD) enzyme is responsible for the detoxifying metabolism of fluoropyrimidines, a class of drugs that includes 5-Fluorouracil, Capecitabine, and Tegafur. Genetic variations within the DPD gene can lead to reduced or absent DPD activity, and individuals who are heterozygous or homozygous for these variations may have partial or complete DPD deficiency; an estimated 0.2% of individuals have complete DPD deficiency. Those with partial or complete DPD deficiency have a significantly increased risk of severe or even fatal drug toxicities when treated with fluoropyrimidines; examples of toxicities include myelosuppression, neurotoxicity and hand-foot syndrome.

Frequently Asked Questions

  • What is the cost of DPD GENE MUTATIONS (5-FU TOXICITY) DETECTION Test?

    Cost of DPD GENE MUTATIONS (5-FU TOXICITY) DETECTION Test is 9828 Rs

₹9,828.00 ₹10,920.0010% off

Book Now
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