Extended AML Panel (BCR/ABL,AML/ETO, CBFB, PML/RARA, FLT3, NPM1, CEBPA) Test
Short Name: Extended AML Panel
Also known as: AML Genetic Panel, Leukemia Mutation Panel
Extended AML Panel (BCR/ABL,AML/ETO, CBFB, PML/RARA, FLT3, NPM1, CEBPA) Test test available at DNA Labs India for ₹27,000. Uses Sanger Sequencing on Bone marrow / Peripheral blood samples. Results in 7-8 days from sample collection. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the Extended AML Panel is to detect genetic mutations in genes such as BCR/ABL, AML/ETO, CBFB, PML/RARA, FLT3, NPM1, and CEBPA, which are associated with Acute Myeloid Leukemia. This helps in confirming diagnosis, determining prognosis, guiding targeted therapy, monitoring treatment efficacy, and identifying potential relapse.
- Test Code
- 2994
- Price
- ₹27,000
- Sample Type
- Bone marrow / Peripheral blood
- Result Time
- 7-8 days from sample collection
- Fasting Required
- No
- Method
- Sanger Sequencing
Sample Collection
No specific preparation required. Ensure a doctor's prescription is available if needed.
Method: Venipuncture
Laboratory Analysis
Sample collected via venipuncture from bone marrow or peripheral blood. Transport immediately to lab.
Report Delivery
Apply pressure to the puncture site to prevent bruising. Resume normal activities unless advised otherwise.
Timeline: 7-8 days from sample collection
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Extended AML Panel is to detect genetic mutations in genes such as BCR/ABL, AML/ETO, CBFB, PML/RARA, FLT3, NPM1, and CEBPA, which are associated with Acute Myeloid Leukemia. This helps in confirming diagnosis, determining prognosis, guiding targeted therapy, monitoring treatment efficacy, and identifying potential relapse.
How to Prepare
- Use EDTA Vacutainer (2ml) for sample collection.
- Transport sample immediately to maintain stability.
- Ensure proper labeling and documentation.
- Home collection available with cool pack for preservation.
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This panel is crucial for accurate diagnosis, prognosis, and personalized treatment planning in Acute Myeloid Leukemia, helping to identify specific mutations that guide therapy decisions."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted samples
- Insufficient sample volume
- Improper container or labeling
- Delayed transport beyond stability period
Understanding Your Results
Mutation Detected
Presence of a specific mutation (e.g., FLT3, NPM1) may influence prognosis and therapy, such as targeted drugs.
No Mutation Detected
Absence of tested mutations does not rule out AML; other genetic or cytogenetic abnormalities may be present.
Fusion Gene Positive
Fusion genes like BCR/ABL or PML/RARA indicate specific AML subtypes with distinct treatment protocols.
Consult a hematologist or oncologist if you experience symptoms of AML, have abnormal blood test results, or need guidance on treatment based on panel findings.
Limitations
- ⚠May not detect all rare or novel mutations
- ⚠Requires expert interpretation by geneticists
- ⚠Results should be correlated with clinical findings and other tests
- ⚠False negatives possible in low mutation burden cases
Risks & Considerations
- ●Minor pain or bruising at puncture site
- ●Rare risk of infection with bone marrow biopsy
- ●No significant risks for blood draw
Interfering Factors
- ●Sample contamination
- ●Improper sample storage or transport
- ●Recent blood transfusions affecting DNA quality
- ●Technical errors in sequencing
Compare With Similar Tests
| Test | Extended AML Panel (BCR/ABL,AML/ETO, CBFB, PML/RARA, FLT3, NPM1, CEBPA) | Complete Blood Count (CBC) | Bone Marrow Biopsy | Cytogenetic Analysis | FLT3 Single Gene Test |
|---|---|---|---|---|---|
| Comparison | Extended AML Panel (BCR/ABL,AML/ETO, CBFB, PML/RARA, FLT3, NPM1, CEBPA) |
Frequently Asked Questions
What is the Extended AML Panel test?
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