GJB6 Gene Deafness: Understanding Autosomal Recessive Type 1B NGS Genetic Test
Deafness is a condition that affects millions of people worldwide. It can be caused by a variety of factors, including genetic mutations. One of the most common causes of genetic deafness is the GJB6 gene mutation. This mutation is responsible for autosomal recessive type 1B (DFNB1B) deafness, which affects approximately 1 in 20,000 individuals.
Understanding GJB6 Gene Deafness
The GJB6 gene is responsible for producing a protein called connexin 30. This protein is essential for the proper functioning of the inner ear. When the GJB6 gene is mutated, it can lead to a reduction or absence of connexin 30, which can cause deafness.
Autosomal recessive type 1B (DFNB1B) deafness is inherited in an autosomal recessive manner, which means that an individual must inherit two copies of the mutated gene – one from each parent – to develop the condition. If an individual inherits only one copy of the mutated gene, they are considered a carrier of the condition and will not typically experience any symptoms.
Symptoms of GJB6 Gene Deafness
The symptoms of GJB6 gene deafness can vary from person to person. Some individuals may experience mild to moderate hearing loss, while others may be completely deaf. The severity of the condition can depend on a variety of factors, including the specific mutation and the age of onset.
Some common symptoms of GJB6 gene deafness include:
- Hearing loss
- Tinnitus (ringing in the ears)
- Difficulty understanding speech, especially in noisy environments
- Sensitivity to loud noises
- Difficulty hearing high-pitched sounds
Diagnosis of GJB6 Gene Deafness
The diagnosis of GJB6 gene deafness typically involves a combination of a physical examination, a hearing test, and genetic testing.
A hearing test, also known as an audiogram, is used to evaluate the extent of hearing loss. This test involves wearing headphones and listening to sounds at different frequencies and volumes.
Genetic testing can be used to confirm a diagnosis of GJB6 gene deafness. This test involves analyzing a sample of an individual’s DNA to look for mutations in the GJB6 gene. Next-generation sequencing (NGS) is a type of genetic testing that can analyze multiple genes simultaneously and can be used to diagnose a variety of genetic conditions.
Cost of NGS Genetic Test for GJB6 Gene Deafness
The cost of an NGS Genetic Test for GJB6 gene deafness can vary depending on the laboratory and the specific test ordered. However, the average cost of this test in India is approximately INR 20,000.
Conclusion
GJB6 gene deafness is a genetic condition that can cause hearing loss or deafness. It is inherited in an autosomal recessive manner and can be diagnosed through a combination of physical examination, hearing tests, and genetic testing. NGS Genetic Testing is a cost-effective and efficient way to diagnose GJB6 gene deafness. If you or a loved one is experiencing symptoms of hearing loss, it is important to seek medical attention and undergo testing to determine the underlying cause.
Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for GJB6 Gene Deafness, autosomal recessive type 1B NGS Genetic Test
| Test Name | GJB6 Gene Deafness, autosomal recessive type 1B NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | ENT Doctor |
| Pre-test Information | Clinical History of Patient who is going for SLC52A3 Gene Brown-Vialetto-Van Laere syndrome 1 NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with SLC52A3 Gene Brown-Vialetto-Van Laere syndrome 1 NGS Genetic Test gene SLC52A9 |
| Disease | Ear Nose Throat Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for SLC52A3 Gene Brown-Vialetto-Van Laere syndrome 1 NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with SLC52A3 Gene Brown-Vialetto-Van Laere syndrome 1 NGS Genetic Test gene SLC52A9 |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for GJB6 Gene Deafness, autosomal recessive type 1B NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
