Neurodegeneration with Brain Iron Accumulation: Understanding GTPBP2 Gene and NGS Genetic Test Cost
Neurodegeneration with Brain Iron Accumulation (NBIA) is a group of rare genetic disorders that affect the brain. These disorders are characterized by an abnormal accumulation of iron in the brain and progressive degeneration of the nervous system. One of the genes associated with NBIA is the GTPBP2 gene. Mutations in this gene have been linked to NBIA and related disorders.
GTPBP2 Gene and NBIA
The GTPBP2 gene provides instructions for making a protein that is involved in the production of iron-sulfur clusters. Iron-sulfur clusters are critical components of many proteins that play important roles in various cellular processes, including energy production and DNA repair. Mutations in the GTPBP2 gene can lead to a decrease in the production of iron-sulfur clusters, which can result in the accumulation of iron in the brain.
The accumulation of iron in the brain can lead to a range of neurological symptoms, including movement disorders, cognitive impairment, and seizures. These symptoms can vary in severity and can worsen over time.
NGS Genetic Test Cost for GTPBP2-related NBIA
NGS Genetic Testing is a powerful tool for diagnosing genetic disorders. This type of testing can detect mutations in the GTPBP2 gene and other genes associated with NBIA. The cost of an NGS Genetic Test for GTPBP2-related NBIA can vary depending on the testing facility and the specific tests performed.
At DNA Labs India, the cost of an NGS Genetic Test for GTPBP2-related NBIA is INR 20000. This test can help diagnose NBIA and related disorders, allowing for earlier intervention and treatment.
Symptoms and Diagnosis of GTPBP2-related NBIA
The symptoms of GTPBP2-related NBIA can vary depending on the specific mutation and the severity of the disorder. Some common symptoms include:
- Movement disorders, such as dystonia and Parkinsonism
- Cognitive impairment and developmental delays
- Seizures
- Visual disturbances
- Speech difficulties
Diagnosing GTPBP2-related NBIA typically involves a combination of clinical evaluation, imaging studies, and genetic testing. An NGS Genetic Test can detect mutations in the GTPBP2 gene and other genes associated with NBIA, providing a definitive diagnosis.
Conclusion
GTPBP2-related NBIA is a rare genetic disorder that can cause a range of neurological symptoms. NGS Genetic Testing is a powerful tool for diagnosing this disorder and can help identify mutations in the GTPBP2 gene and other genes associated with NBIA. At DNA Labs India, the cost of an NGS Genetic Test for GTPBP2-related NBIA is INR 20000. Early diagnosis and intervention can help improve outcomes for individuals with this disorder, making genetic testing an important tool for healthcare providers.
For more information on genetic testing and NBIA, please visit the DNA Labs India website.
Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for GTPBP2 Gene Neurodegeneration with brain iron accumulation, GTPBP2 related NGS Genetic Test
| Test Name | GTPBP2 Gene Neurodegeneration with brain iron accumulation, GTPBP2 related NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card o |
| Test type | Neurologist |
| Pre-test Information | Clinical History of Patient who is going for GTPBP2 Gene Neurodegeneration with brain iron accumulation, GTPBP2 related NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with GTPBP2 Gene Neurodegeneration with brain iron accumulation, GTPBP2 related |
| Disease | Neurological Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for GTPBP2 Gene Neurodegeneration with brain iron accumulation, GTPBP2 related NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with GTPBP2 Gene Neurodegeneration with brain iron accumulation, GTPBP2 related |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for GTPBP2 Gene Neurodegeneration with brain iron accumulation, GTPBP2 related NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
