ITGAM Gene and Systemic Lupus Erythematosus: Understanding Susceptibility and Diagnosis through NGS Genetic Test
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organ systems and can cause inflammation and damage to different parts of the body. According to the Lupus Foundation of America, approximately 1.5 million Americans and 5 million people worldwide have lupus.
The exact cause of lupus is not fully understood, but genetic factors are believed to play a role in the development of the disease. One of the genes associated with lupus susceptibility is the ITGAM gene, which codes for a protein called integrin alpha M (CD11b).
The Role of ITGAM Gene in Lupus
The ITGAM gene is located on chromosome 16 and is involved in the immune system’s response to infections and foreign substances. The CD11b protein is expressed on the surface of immune cells, including macrophages, dendritic cells, and neutrophils, and helps these cells attach to and engulf foreign particles.
Studies have shown that variations in the ITGAM gene increase the risk of developing lupus. These variations can affect the function of the CD11b protein, leading to abnormal immune responses and inflammation.
NGS Genetic Test for Lupus Diagnosis
Lupus is a complex disease, and its diagnosis can be challenging. The symptoms of lupus can vary widely and can be similar to those of other autoimmune and inflammatory conditions.
NGS (Next Generation Sequencing) Genetic Test is a powerful tool for detecting genetic variations associated with lupus susceptibility, including variations in the ITGAM gene. The test analyzes the patient’s DNA sample and identifies variations in specific genes that increase the risk of developing lupus.
The NGS Genetic Test can also help diagnose lupus in patients with unclear symptoms. The test can identify genetic variations that are specific to lupus and distinguish them from other autoimmune and inflammatory conditions.
Cost and Availability of NGS Genetic Test in India
The cost of NGS Genetic Test for lupus diagnosis in India is approximately INR 20,000. The test is available at several DNA labs in India, including DNA Labs India.
DNA Labs India is a leading provider of genetic testing services in India, offering a wide range of DNA tests, including NGS Genetic Test for lupus diagnosis. The lab is equipped with state-of-the-art technology and staffed by experienced geneticists and technicians, ensuring accurate and reliable results.
Conclusion
NGS Genetic Test is a valuable tool for understanding the genetic factors that contribute to lupus susceptibility and for diagnosing the disease. The ITGAM gene is one of the genes associated with lupus susceptibility, and variations in this gene can affect the function of the CD11b protein and lead to abnormal immune responses and inflammation.
DNA Labs India offers NGS Genetic Test for lupus diagnosis at an affordable cost, making it accessible to patients in India. The test can help diagnose lupus in patients with unclear symptoms and provide valuable information for the management and treatment of the disease.
Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for ITGAM Gene Systemic lupus erythematosus, susceptibility to NGS Genetic Test
| Test Name | ITGAM Gene Systemic lupus erythematosus, susceptibility to NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | Dermatologist |
| Pre-test Information | Clinical History of Patient who is going for ITGAM Gene Systemic lupus erythematosus, susceptibility to NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with ITGAM Gene Systemic lupus erythematosus, susceptibility to NGS Genetic Test gene ITGAM |
| Disease | Osteology Dermatology Immunology Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for ITGAM Gene Systemic lupus erythematosus, susceptibility to NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with ITGAM Gene Systemic lupus erythematosus, susceptibility to NGS Genetic Test gene ITGAM |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for ITGAM Gene Systemic lupus erythematosus, susceptibility to NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
