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Lupus Anticoagulant by dRVVT Test

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Lupus Anticoagulant by dRVVT Test

Short Name: Lupus Anticoagulant dRVVT Test

Also known as: dRVVT Test, Dilute Russell Viper Venom Time Test

Lupus Anticoagulant by dRVVT Test test available at DNA Labs India for ₹1,989. Uses Electromechanical Clot Detection on Whole blood samples. Results in Sample collection daily by 3 pm; report available next day.. Free home collection in 300+ cities across India.

Hematology TestAdults🏠 Home Collection

🩺 Medically Reviewed By

Overview

To diagnose lupus anticoagulant by evaluating the clotting time of blood using dilute Russell viper venom, aiding in the identification of thromboembolic disorders.

Test Code
1193
Price
₹1,989
Sample Type
Whole blood
Result Time
Sample collection daily by 3 pm; report available next day.
Fasting Required
Yes (8 hours)
Method
Electromechanical Clot Detection
Step 1

Sample Collection

Overnight fasting is preferred. Discontinue heparin for 1 day and oral anticoagulants for 7 days prior to sampling, with prior consent from your treating physician. Duly filled Coagulation Requisition Form (Form 15) is mandatory.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be drawn via venipuncture into a blue top (sodium citrate) tube and mixed thoroughly by inversion.

Step 3

Report Delivery

The sample should be transported to the lab within 4 hours. If delayed, prepare platelet-poor plasma (PPP) by double centrifugation and freeze immediately.

Timeline: Sample collection daily by 3 pm; report available next day.

Patient Instructions

1
Before the Test:Fast overnight and follow medication discontinuation guidelines as advised by your physician.
2
During the Test:A small blood sample is drawn from a vein in your arm using a needle.
3
After the Test:Apply pressure to the puncture site to stop bleeding; resume normal activities unless otherwise instructed.

About This Test

Who Should Get This Test

To diagnose lupus anticoagulant by evaluating the clotting time of blood using dilute Russell viper venom, aiding in the identification of thromboembolic disorders.

How to Prepare

  • Collect 3 mL of whole blood in a blue top (sodium citrate) tube.
  • Mix thoroughly by inversion to prevent clotting.
  • Transport to lab within 4 hours. If not possible, prepare PPP: centrifuge at 3600 rpm for 15 minutes, transfer supernatant, centrifuge again, and freeze.
  • Ship frozen; do not thaw.

Doctor's Notes

Reviewed by — MBBS, MD (Haematology) · Reg. No. AMC4946

"The dRVVT test is a critical diagnostic tool for lupus anticoagulant, which can lead to serious thromboembolic events. Timely diagnosis and management are essential."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeWhole blood
Sample Volume3 mL
ContainerBlue Top (Sodium Citrate) tube
Collection MethodVenipuncture

Sample Stability

Room Temperature
Refrigerator
Frozen
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Incorrect tube type or insufficient volume
  • Samples not processed or stored as instructed
  • Missing Coagulation Requisition Form (Form 15)

Understanding Your Results

The dRVVT test measures the time for blood to clot; prolonged clotting time suggests the presence of lupus anticoagulant, which may indicate an increased risk of blood clots.
Normal dRVVT time: Lupus anticoagulant likely not detected.
Prolonged dRVVT time: Possible lupus anticoagulant; mixing studies may be recommended for confirmation.
Results should be interpreted alongside clinical symptoms and other coagulation tests.
⚠️ When to Consult a Doctor:

If you experience symptoms such as unexplained swelling, pain, shortness of breath, or recurrent clots, or if your dRVVT test results are abnormal, consult a hematologist or physician for further evaluation.

Limitations

  • False positives may occur in some inflammatory conditions
  • Results require clinical correlation for diagnosis
  • Not standalone for LA diagnosis; often used with other tests

Risks & Considerations

  • Minor bruising or discomfort at the blood draw site
  • Rare risk of infection or dizziness

Interfering Factors

  • Use of heparin within 1 day of testing
  • Use of oral anticoagulants (e.g., warfarin) within 7 days of testing
  • Lipemic, hemolyzed, or clotted blood samples

Compare With Similar Tests

TestLupus Anticoagulant by dRVVT TestActivated Partial Thromboplastin Time (aPTT)Prothrombin Time (PT)Thrombin Time (TT)
ComparisonLupus Anticoagulant by dRVVT Test

Frequently Asked Questions

What is the cost of the Lupus Anticoagulant by dRVVT Test?
The test costs INR 1989 at DNA Labs India, inclusive of home collection and specialist consultation.
What does the dRVVT test diagnose?
It diagnoses lupus anticoagulant, an autoimmune condition that increases the risk of blood clots.
How is the dRVVT test performed?
A blood sample is mixed with Russell viper venom, and the clotting time is measured to detect lupus anticoagulant.
What are the symptoms of lupus anticoagulant?
Symptoms may include unexplained leg swelling, shortness of breath, frequent headaches, fatigue, and skin rashes.
How should I prepare for the dRVVT test?
Fast overnight, and discontinue heparin for 1 day and oral anticoagulants for 7 days prior, with physician consent.
Is fasting required for the dRVVT test?
Yes, overnight fasting is preferred to ensure accurate results.
What sample type is used for the dRVVT test?
3 mL of whole blood in a blue top (sodium citrate) tube.
How long does it take to get dRVVT test results?
Results are typically available the next day after sample collection.
Are there any risks with the dRVVT test?
Risks are minimal, such as minor bruising or dizziness from the blood draw.
What if my dRVVT test results are abnormal?
Consult a hematologist or physician for further evaluation, as abnormal results may indicate lupus anticoagulant.
Can I take medications before the dRVVT test?
Certain medications like heparin or oral anticoagulants should be discontinued as advised to avoid interference.
Is home collection available for the dRVVT test?
Yes, DNA Labs India offers free home sample collection for this test across numerous cities in India.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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