NDUFA2 Gene Leigh Syndrome NGS Genetic Test Cost INR: 20000 Symptoms Diagnosis
Leigh syndrome is a rare genetic disorder that affects the central nervous system. The disease is named after Dr. Archibald Denis Leigh, who first described the condition in 1951. The disease is caused by mutations in the mitochondrial DNA or nuclear DNA. NDUFA2 is one of the nuclear genes that are associated with Leigh syndrome. In this blog, we will discuss the NDUFA2 gene, Leigh syndrome, its symptoms, diagnosis, and the cost of the NGS Genetic Test in India.
NDUFA2 Gene
The NDUFA2 gene is located on chromosome 18 and encodes a subunit of complex I of the mitochondrial respiratory chain. Complex I is the first complex in the electron transport chain, which is responsible for generating energy in the form of ATP. Mutations in the NDUFA2 gene can cause Leigh syndrome, which is characterized by progressive neurological symptoms.
Leigh Syndrome
Leigh syndrome is a progressive neurological disorder that typically begins in infancy or early childhood. The disease is caused by mutations in mitochondrial or nuclear DNA that affect the function of the mitochondrial respiratory chain. As a result, the affected cells cannot generate enough energy, which leads to cell death and progressive neurological symptoms.
Symptoms of Leigh Syndrome
The symptoms of Leigh syndrome can vary widely depending on the affected individual. Some of the common symptoms include:
- Developmental delay
- Weakness and fatigue
- Poor feeding and vomiting
- Seizures
- Loss of motor skills
- Respiratory failure
- Visual and hearing impairment
Diagnosis of Leigh Syndrome
The diagnosis of Leigh syndrome involves a combination of clinical evaluation, laboratory tests, and imaging studies. The clinical evaluation may include a thorough medical history, physical examination, and neurological assessment. Laboratory tests may include blood tests, urine tests, and genetic testing to identify mutations in mitochondrial or nuclear DNA. Imaging studies such as MRI and CT scans may also be performed to evaluate the brain and other organs.
NGS Genetic Test Cost in India
The cost of the NGS Genetic Test for Leigh syndrome in India may vary depending on the laboratory and location. However, on average, the cost of the test may range from INR 15,000 to INR 25,000. It is important to note that some insurance companies may cover the cost of genetic testing, so it is always recommended to check with your insurance provider before undergoing any genetic testing.
Conclusion
Leigh syndrome is a rare genetic disorder that can be caused by mutations in the NDUFA2 gene. The disease is characterized by progressive neurological symptoms that can be diagnosed through a combination of clinical evaluation, laboratory tests, and imaging studies. The cost of the NGS Genetic Test for Leigh syndrome in India may vary, but it is an important tool for early diagnosis and management of the disease. If you suspect that you or a family member may have Leigh syndrome, it is important to consult a genetic counselor or healthcare professional for further evaluation and testing.
For more information on genetic testing and DNA labs in India, visit
DNA Labs India
.
Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for NDUFA2 Gene Leigh syndrome NGS Genetic Test
| Test Name | NDUFA2 Gene Leigh syndrome NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card o |
| Test type | Neurologist |
| Pre-test Information | Clinical History of Patient who is going for NDUFA2 Gene Leigh syndrome NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with NDUFA2 Gene Leigh syndrome |
| Disease | Neurological Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for NDUFA2 Gene Leigh syndrome NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with NDUFA2 Gene Leigh syndrome |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for NDUFA2 Gene Leigh syndrome NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
