Comprehensive Hereditary Cancer Risk Panel (190 Genes) | DNA Labs India

Understand Your Inherited Cancer Risk with Advanced Genetic Insights

The OncoPro Hereditary Cancer Risk Panel Test at DNA Labs India is a state-of-the-art genetic analysis designed to identify inherited mutations across 190 key genes strongly associated with an increased lifetime risk for various cancers. This comprehensive test provides crucial information that can empower you and your family to make informed decisions about proactive health management, in consultation with your healthcare provider.

Exclusive 2026 Price: ₹24,999 (A comprehensive panel covering 190 genes).

🔬 What is the Hereditary Cancer Risk Panel?

Cancer can sometimes run in families due to specific changes (mutations) in genes that are passed down from parents to children. The OncoPro Panel uses Next-Generation Sequencing (NGS) technology to meticulously examine 190 genes scientifically validated for their link to hereditary cancer syndromes.

This test is not a diagnostic tool for active cancer. Instead, it is a predictive risk assessment tool. Identifying a pathogenic mutation means you have an increased risk of developing certain cancers in your lifetime, allowing for earlier, more personalized screening and prevention strategies.

👨‍👩‍👧‍👦 Who Should Consider This Test?

This test may be particularly relevant if you have a personal or family history that includes:

• Multiple relatives on the same side of the family with the same or related cancers (e.g., breast, ovarian, colorectal).

• Cancer diagnosed at unusually young ages.

• Rare cancers or multiple primary cancers in one individual.

• A known hereditary cancer mutation in the family.

• Strong anxiety about family cancer history, seeking clarity for future planning.

A genetic counseling session before and after testing is highly recommended to understand the implications, benefits, and limitations of the results for you and your family.

📋 Test Details & Process

• Test Name: OncoPro Hereditary Cancer Risk Panel Test

• Sample Required: Blood (3-5 ml in an EDTA vial) or Buccal Swab (cheek swab). A blood sample drawn by a phlebotomist is often preferred for optimal DNA yield.

• Methodology: Next-Generation Sequencing (NGS) with Sanger sequencing confirmation for specific findings.

• Report Time: 21 Days from sample receipt at our lab.

• Pre-test Information: Fasting is not required. Please inform us of any ongoing medications.

Genes Analyzed in the Test

The test examines a broad spectrum of genes associated with cancer risk. Some key genes include:

• BRCA1 and BRCA2 (linked to breast and ovarian cancer)
• APC (associated with colorectal cancer)
• TP53 (involved in multiple cancer types)
• MLH1 and MSH2 (related to Lynch syndrome)

The test examines a broad spectrum of genes associated with cancer risk. Here is the complete list of genes included:

• ABRAXAS1, AIP, AKT1
• ALK, *APC, AR
• ATM, AXIN2, BAP1
• BARD1, BLM, BMPR1A
• BRCA1, BRCA2, BRIP1
• BUB1B, CBL, CD82
• CDC73, CDH1, CDK12
• CDK4, CDKN1B, CDKN1C
• CDKN2A, CEBPA, CEP57
• CHEK1, CHEK2, CTNNA1
• CUL2, CYLD, DDB2
• DDX41, DICER1, DIS3
• DIS3L2, EGFR, ELAC2
• ENG, EPCAM, ERBB2
• ERCC2, ERCC3, ERCC4
• ERCC5, ESR2, EXT1
• EXT2, EZH2, FAN1
• FANCA to FANCM (FANCB through FANCL)
• FH, FLCN
• GALNT12 to GFAP (GATA2)
• GPC3 to HNF1B (HNF1A)
• HOXB13 to KIF1B (HRAS)
• KIT to MAX (LZTR1)
• MED12 to MET (MEN1)
• MITF to MLH3 (MLH1)
• MRE11 to MUTYH (MSH6)
• MXI1 to NF1 (NBN)
• NF2 to NSD1 (NOTCH1)
• NTHL1 to PALLD (PALB2)
• PAX5 to PDGFRA (PBRM1)
• PHOX2B to PMS2 (PMS1)
• POLD1 to POT1 (POLE)
• PPP2R2A to PRKAR1A (PRF1)
• PRSS1 to PTCH2 (PTCH1)
• PTEN to RAD54L (RAD51D)
• RB1 to RECQL4 (RECQL)
• RET to RINT1 (RHBDF2)
• RNASEL to RNF43 (RNF139)
• RUNX1 to SDHC (SBDS through SDHB)
• SDHD to SLC45A2 (SETD2)
• SLX4 to SMARCE1 (SMAD4 through SMARCB1)
• SPOP to SUFU (SRGAP1 through STK11)
• *TERT to TMEM127 (TGFBR2)
• TP53 to TSC2 (TSC1)
• TYR to XPC (VHL through WRN)

🧪 What Does the Test Analyze?

The panel screens for mutations in genes linked to a wide spectrum of hereditary cancer syndromes, including but not limited to:

• Hereditary Breast and Ovarian Cancer (HBOC): BRCA1, BRCA2, PALB2, ATM, CHEK2

• Lynch Syndrome (Hereditary Non-Polyposis Colorectal Cancer): MLH1, MSH2, MSH6, PMS2, EPCAM

• Li-Fraumeni Syndrome: TP53

• Familial Adenomatous Polyposis (FAP): APC

• And many more genes associated with renal, pancreatic, gastric, prostate, and endocrine cancers.

📈 Why Choose DNA Labs India for Your Genetic Testing?

1. Comprehensive & Precise: Our 190-gene panel is among the most extensive available in India, offering a broad yet deep analysis for peace of mind.

2. ISO-Accredited Quality: Our laboratory processes adhere to stringent international quality standards. We are proud to hold ISO 9001:2015 certification for clinical sample testing and reporting. You can view our certificate of registration here.

3. Expert Analysis & Confidentiality: Your sample is processed in our advanced Hyderabad facility by experienced genetic scientists. Patient confidentiality and data security are our utmost priorities.

4. Clear, Actionable Reporting: You will receive a detailed, yet understandable report. We emphasize the importance of sharing this report with your oncologist or genetic counselor to develop a personalized surveillance plan.

❓ Frequently Asked Questions (FAQs)

Q1: If I test positive for a mutation, does it mean I will definitely get cancer?
A: No. A positive result indicates a significantly increased predisposition or risk, not a certainty. It allows you and your doctor to implement enhanced screening (like more frequent mammograms or colonoscopies) and discuss potential risk-reduction strategies.

Q2: What if my test results are negative?
A: A “true negative” result (where a known family mutation is not found) can provide significant reassurance. However, a negative result in someone without a known family mutation does not rule out all genetic or environmental cancer risks. Your overall risk becomes similar to that of the general population.

Q3: Can this test detect all types of cancer?
A: No. This test is specifically designed to detect inherited mutations for hereditary cancer syndromes. It does not screen for acquired (somatic) mutations that cause the majority of cancers, nor does it diagnose existing cancer.

Q4: Should I consider testing if no one in my family had cancer?
A: In the absence of a strong personal or family history, the likelihood of finding a harmful mutation is lower. Testing in such scenarios should be discussed thoroughly with a genetic counselor to set appropriate expectations.

Q5: What are my options if a mutation is found?
A: Management options vary and are personalized. They may include increased surveillance, preventive surgeries (e.g., mastectomy, oophorectomy), lifestyle modifications, and family testing. Your doctor or counselor will guide you.

🔗 Taking the Next Step

Understanding your genetic blueprint is a powerful step toward taking control of your health. The OncoPro Hereditary Cancer Risk Panel provides the information needed to move from uncertainty to a proactive plan.

We recommend discussing this test with your physician or a genetic counselor. If you are ready to proceed, DNA Labs India is here to support you with accurate testing and clear reporting.

To book your OncoPro Hereditary Cancer Risk Panel Test or learn more about our other genetic tests, such as our Home DNA Test Kit, please contact our customer support.

Disclaimer: This test is for informational and risk assessment purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your qualified physician or genetic counselor with any questions you may have regarding a medical condition or before starting any new health plan.

 Note: We offer free home sample collection for online bookings for Comprehensive Hereditary Cancer Panel (150 Genes) Test and the test costs a special discounted price of 25000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.