Comprehensive Hereditary Cancer Panel (190 Genes) Test Price 25000 INR
Cancer is one of the most dreaded diseases known to mankind. Hereditary cancer is a type of cancer that is caused by genetic mutations passed down from parents to their children. The Comprehensive Hereditary Cancer Panel (190 Genes) test is a genetic test that can help identify individuals who are at an increased risk of developing hereditary cancers.
Understanding your genetic predisposition to hereditary cancers can be a game-changer in managing your health. The Comprehensive Hereditary Cancer Panel, which analyzes 190 genes, offers a thorough assessment of your risk for 25 different types of hereditary cancers. This test is grounded in the latest NCCN guidelines and peer-reviewed research, ensuring its reliability and relevance.
Symptoms of Cancer:
Cancer can manifest in a variety of ways. Some of the most common symptoms of hereditary cancer include:
- Unexplained weight loss
- Unexplained fatigue
- Changes in bowel or bladder habits
- A persistent cough or hoarseness
- Difficulty swallowing
- Unexplained bleeding or bruising
The Comprehensive Hereditary Cancer Panel (190 Genes) test is a vital resource for individuals in India seeking to understand their risk of hereditary cancers. Offered by DNA Labs India at a cost of ₹25,000, this test examines 190 genes linked to 25 different hereditary cancers, providing a thorough risk assessment based on NCCN guidelines and peer-reviewed studies.
Why Consider the Comprehensive Hereditary Cancer Panel?
Hereditary cancers are caused by genetic mutations inherited from one’s parents. Identifying these mutations can:
- Enable early detection and intervention.
- Inform personalized screening and prevention strategies.
- Offer peace of mind or prompt further investigation if there is a family history of cancer.
- Facilitate Early Detection: Knowing your genetic risk allows for proactive monitoring and early intervention.
- Guide Personalized Healthcare: Tailor your screening and prevention strategies based on your genetic profile.
- Provide Peace of Mind: Understanding your genetic risks can alleviate anxiety and guide informed decisions.
Cancers Covered by the Test:
This panel targets a wide array of cancers, including:
- Breast, Ovarian, Uterine
- Stomach, Endocrine Pancreas, Esophagus
- Colorectal, Endometrium, Bone
- Thyroid, Kidneys, Urinary Tract
- Lung, Prostate, Central Nervous System
- Head & Neck, Liver, Cervix
- Exocrine Pancreas, Small Intestine
- Blood, Soft Tissue, Skin
- Peripheral Nervous System & Endocrine Glands
Genes Analyzed in the Test”
The test examines a broad spectrum of genes associated with cancer risk. Some key genes include:
- BRCA1 and BRCA2 (linked to breast and ovarian cancer)
- APC (associated with colorectal cancer)
- TP53 (involved in multiple cancer types)
- MLH1 and MSH2 (related to Lynch syndrome)
The test examines a broad spectrum of genes associated with cancer risk. Here is the complete list of genes included:
- ABRAXAS1, AIP, AKT1
- ALK, *APC, AR
- ATM, AXIN2, BAP1
- BARD1, BLM, BMPR1A
- BRCA1, BRCA2, BRIP1
- BUB1B, CBL, CD82
- CDC73, CDH1, CDK12
- CDK4, CDKN1B, CDKN1C
- CDKN2A, CEBPA, CEP57
- CHEK1, CHEK2, CTNNA1
- CUL2, CYLD, DDB2
- DDX41, DICER1, DIS3
- DIS3L2, EGFR, ELAC2
- ENG, EPCAM, ERBB2
- ERCC2, ERCC3, ERCC4
- ERCC5, ESR2, EXT1
- EXT2, EZH2, FAN1
- FANCA to FANCM (FANCB through FANCL)
- FH, FLCN
- GALNT12 to GFAP (GATA2)
- GPC3 to HNF1B (HNF1A)
- HOXB13 to KIF1B (HRAS)
- KIT to MAX (LZTR1)
- MED12 to MET (MEN1)
- MITF to MLH3 (MLH1)
- MRE11 to MUTYH (MSH6)
- MXI1 to NF1 (NBN)
- NF2 to NSD1 (NOTCH1)
- NTHL1 to PALLD (PALB2)
- PAX5 to PDGFRA (PBRM1)
- PHOX2B to PMS2 (PMS1)
- POLD1 to POT1 (POLE)
- PPP2R2A to PRKAR1A (PRF1)
- PRSS1 to PTCH2 (PTCH1)
- PTEN to RAD54L (RAD51D)
- RB1 to RECQL4 (RECQL)
- RET to RINT1 (RHBDF2)
- RNASEL to RNF43 (RNF139)
- RUNX1 to SDHC (SBDS through SDHB)
- SDHD to SLC45A2 (SETD2)
- SLX4 to SMARCE1 (SMAD4 through SMARCB1)
- SPOP to SUFU (SRGAP1 through STK11)
- *TERT to TMEM127 (TGFBR2)
- TP53 to TSC2 (TSC1)
- TYR to XPC (VHL through WRN)
How is the Test Conducted?
The test requires a blood sample and utilizes Next Generation Sequencing (NGS) technology to analyze DNA for mutations across the selected 150 genes. Results are typically available within four weeks.
Cost of the Test in India
Priced at ₹25,000 at DNA Labs India, this test represents a significant reduction from its original cost of ₹32,500. While not usually covered by insurance, the investment can be invaluable for those with a family history of cancer.
Benefits of Early Detection
Early detection through genetic testing can lead to:
- Increased surveillance and timely interventions.
- Lifestyle modifications to reduce cancer risk.
- Informed decisions about preventive measures like prophylactic surgeries.
Personal Anecdote: A Journey to Prevention
Consider the story of Rajesh from Bengaluru. With a family history of prostate cancer, he decided to take the Comprehensive Hereditary Cancer Panel test. The results revealed a genetic mutation that increased his risk. This knowledge allowed Rajesh to work with his healthcare provider to implement regular screenings and lifestyle changes that could mitigate his risk.
Conclusion
The Comprehensive Hereditary Cancer Panel (190 Genes) test is an important tool for identifying individuals who are at an increased risk of developing hereditary cancers. If you have a family history of cancer, it may be worth considering this test to help identify your risk and take steps to protect your health.
If you have any concerns about hereditary cancer or the Comprehensive Hereditary Cancer Panel (190 Genes) test, speak to your doctor or a genetic counselor for more information.
Remember, early detection and prevention are key to fighting cancer.
| Test Name | Comprehensive Hereditary Cancer Panel (190 Genes) Test |
|---|---|
| Sample type | Blood |
| Test type | Physician, Oncologist |
| Pre-test Information | A duly filled Oncopro Hereditary Cancer Risk Clinical Information Form (Form 27) is mandatory. |
| Disease | Cancer |
| Method | Next Generation Sequencing |
| Purpose | Screens 190 genes: |
| Preparation | Room Temperature: 72 hrs, Refrigerator:NA, Frozen: NA |
| Fasting | A duly filled Oncopro Hereditary Cancer Risk Clinical Information Form (Form 27) is mandatory. |
| Get Reports | 4 weeks |
| Test Price | ₹ 25000 INR |
Note: We offer free home sample collection for online bookings for Comprehensive Hereditary Cancer Panel (150 Genes) Test and the test costs a special discounted price of 25000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
