Smooth Muscle Antibody (ASMA) IFA in Dilutions Test
Short Name: ASMA IFA in Dilutions
Also known as: ASMA IFA, Smooth Muscle Antibody IFA, Anti-Smooth Muscle Antibody
Smooth Muscle Antibody (ASMA) IFA in Dilutions Test test available at DNA Labs India for ₹4,500. Uses Indirect Immunofluorescence Assay on Serum samples. Results in Reports are usually available the next day after the sample is received by 11 am.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The primary purpose of ASMA IFA in Dilutions is to detect and semi-quantify smooth muscle antibodies in serum. It is particularly useful when chronic active autoimmune hepatitis is suspected in patients with chronic liver disease. It helps guide further investigation and differentiation from viral or alcoholic liver disease.
- Test Code
- 3652
- Price
- ₹4,500
- Sample Type
- Serum
- Result Time
- Reports are usually available the next day after the sample is received by 11 am.
- Fasting Required
- Yes (8 hours)
- Method
- Indirect Immunofluorescence Assay
Sample Collection
Overnight fasting is preferred. Inform your doctor about all current medications and relevant medical history.
Method: Venipuncture
Laboratory Analysis
A trained phlebotomist will collect a venous blood sample from your arm. The procedure takes only a few minutes.
Report Delivery
You can resume normal activities. Press the puncture site gently for a minute to reduce bruising.
Timeline: Reports are usually available the next day after the sample is received by 11 am.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of ASMA IFA in Dilutions is to detect and semi-quantify smooth muscle antibodies in serum. It is particularly useful when chronic active autoimmune hepatitis is suspected in patients with chronic liver disease. It helps guide further investigation and differentiation from viral or alcoholic liver disease.
How to Prepare
- Overnight fasting is preferred before sample collection.
- Carry the test requisition form and any previous liver disease reports.
- Inform the laboratory if you are on immunosuppressive therapy.
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"A positive ASMA titre should always be interpreted as part of the full liver screen, including LFT, viral serology, immunoglobulins, and imaging, rather than as a standalone diagnostic marker."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Grossly haemolysed, lipemic, or icteric serum sample
- Unlabelled or mislabelled sample
- Sample transported at room temperature beyond 6 hours
Understanding Your Results
Consult a gastroenterologist or hepatologist if you have unexplained jaundice, fatigue, abdominal pain, abnormal liver function tests, or an enlarged liver/spleen.
Limitations
- ⚠A positive ASMA result is not specific for autoimmune hepatitis; it can also be positive in primary biliary cirrhosis, chronic viral hepatitis, and alcoholic hepatitis.
- ⚠A negative result does not exclude autoimmune liver disease.
- ⚠The antibody titre alone does not predict disease severity; clinical, biochemical, serological, and histological correlation is essential.
Risks & Considerations
- ●Minor pain or bruising at the needle site
- ●Dizziness or light-headedness
- ●Rare risk of hematoma or infection
Interfering Factors
- ●Recent intravenous immunoglobulin therapy may interfere with antibody detection.
- ●Immunosuppressive or corticosteroid therapy may lower autoantibody titres.
- ●Grossly haemolysed or lipaemic samples may affect immunofluorescence interpretation.
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Frequently Asked Questions
What is the Smooth Muscle Antibody (ASMA) IFA in Dilutions Test?
What disease is this test used to diagnose?
Who should get this test done?
Do I need to fast for this test?
How is the sample collected?
Is home sample collection available?
What is the cost of this test?
How long does the report take?
What is the normal result for this test?
Can this test alone confirm autoimmune hepatitis?
Are there any risks from the blood test?
What are the next steps if the test is positive?
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