TBX3 Gene Ulnar-Mammary Syndrome NGS Genetic Test: Symptoms, Diagnosis, and Cost
Ulnar-Mammary Syndrome (UMS) is a rare genetic disorder that affects the development of limbs, breasts, and teeth. It is caused by mutations in the TBX3 gene, which is responsible for the formation of limbs and other body parts during embryonic development. UMS is inherited in an autosomal dominant pattern, which means that an affected individual has a 50% chance of passing on the condition to their children.
Symptoms of Ulnar-Mammary Syndrome
The symptoms of UMS can vary widely from person to person, even within the same family. Some of the most common symptoms include:
- Missing or underdeveloped fingers or toes
- Underdeveloped breasts or nipples
- Missing or underdeveloped teeth
- Abnormal curvature of the spine
- Small stature
Other symptoms that may occur in some individuals include heart defects, hearing loss, and vision problems.
Diagnosing Ulnar-Mammary Syndrome
UMS is diagnosed through a combination of clinical evaluation and genetic testing. A doctor will typically perform a physical exam to look for characteristic signs of the condition, such as missing or underdeveloped fingers or toes. They may also order imaging tests to evaluate the structure of the limbs and spine.
Genetic testing is the most reliable way to confirm a diagnosis of UMS. This typically involves a Next-Generation Sequencing (NGS) test, which looks for mutations in the TBX3 gene. NGS is a highly accurate and efficient way to sequence large amounts of DNA quickly and cost-effectively.
The Cost of Ulnar-Mammary Syndrome NGS Genetic Test
The cost of a UMS NGS Genetic Test can vary depending on the laboratory performing the test and the specific testing methods used. At DNA Labs India, we offer UMS NGS testing for a cost of INR 20,000.
While this may seem expensive, it is important to remember that genetic testing can provide valuable information about a person’s health and future risk for certain conditions. In the case of UMS, a genetic diagnosis can help individuals and their families make informed decisions about family planning and medical management.
Conclusion
Ulnar-Mammary Syndrome is a rare genetic disorder that can cause a range of developmental abnormalities, including missing or underdeveloped fingers, toes, breasts, and teeth. Diagnosis typically involves a combination of clinical evaluation and genetic testing, with NGS sequencing being the most reliable method for detecting mutations in the TBX3 gene. The cost of UMS NGS testing at DNA Labs India is INR 20,000, which can provide valuable information about a person’s health and future risk for UMS.
If you or a loved one are experiencing symptoms of UMS, or have a family history of the condition, it is important to speak with a doctor or genetic counselor to discuss testing and management options.
Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for TBX3 Gene Ulnar-Mammary syndrome NGS Genetic Test
| Test Name | TBX3 Gene Ulnar-Mammary syndrome NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | Pediatrics |
| Pre-test Information | Clinical History of Patient who is going for TBX3 Gene Ulnar-Mammary syndrome NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with TBX3 Gene Ulnar-Mammary syndrome NGS Genetic Test gene TBX3 |
| Disease | Dysmorphology |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for TBX3 Gene Ulnar-Mammary syndrome NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with TBX3 Gene Ulnar-Mammary syndrome NGS Genetic Test gene TBX3 |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for TBX3 Gene Ulnar-Mammary syndrome NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
