TNFAIP3 Gene and Rheumatoid Arthritis: Symptoms, Diagnosis, and NGS Genetic Test Cost

Rheumatoid arthritis is a chronic autoimmune disorder that primarily affects the joints. It is characterized by inflammation, pain, stiffness, and swelling in the affected joints. While the exact cause of rheumatoid arthritis is not known, genetic factors are believed to play a significant role in its development. One such gene that has been linked to rheumatoid arthritis is TNFAIP3.

TNFAIP3 Gene and Rheumatoid Arthritis

The TNFAIP3 gene, also known as A20, is responsible for producing a protein that regulates the immune system. This protein helps to prevent excessive inflammation and damage to the body’s own tissues. In people with rheumatoid arthritis, there is a mutation in the TNFAIP3 gene that leads to reduced production of the A20 protein. This, in turn, results in increased inflammation and damage to the joints.

Symptoms of Rheumatoid Arthritis

The symptoms of rheumatoid arthritis can vary from person to person. However, some common symptoms include:

• Pain and stiffness in the joints, especially in the morning or after periods of inactivity
• Swelling and tenderness in the joints
• Reduced range of motion in the affected joints
• Fatigue and general weakness
• Fever and weight loss (in severe cases)

Diagnosis of Rheumatoid Arthritis

Diagnosing rheumatoid arthritis can be challenging, as its symptoms are similar to those of other conditions. However, some tests can help to confirm the diagnosis, including:

• Blood tests to detect the presence of rheumatoid factor and anti-cyclic citrullinated peptide (anti-CCP) antibodies
• Imaging tests such as X-rays, MRI, and ultrasound to assess joint damage and inflammation
• Physical examination to assess joint tenderness, swelling, and range of motion

NGS Genetic Test Cost

NGS Genetic Test is a diagnostic test that uses Next Generation Sequencing (NGS) technology to analyze a patient’s DNA. This test can help to identify mutations in the TNFAIP3 gene that may be associated with rheumatoid arthritis. The cost of NGS Genetic Test for TNFAIP3-related rheumatoid arthritis in India is approximately INR 20,000.

Conclusion

Rheumatoid arthritis is a debilitating condition that can significantly impact a person’s quality of life. Understanding the role of genes such as TNFAIP3 in its development can help to improve diagnosis and treatment. If you are experiencing symptoms of rheumatoid arthritis, it is essential to consult a healthcare professional for proper diagnosis and management.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for TNFAIP3 Gene Rheumatoid arthritis, TNFAIP3 related NGS Genetic Test

 Note: We offer free home sample collection for online bookings for TNFAIP3 Gene Rheumatoid arthritis, TNFAIP3 related NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.