TTBK2 Gene Spinocerebellar Ataxia Type 11 – Symptoms, Diagnosis, and NGS Genetic Test Cost
Spinocerebellar ataxia type 11 (SCA11) is a neurodegenerative disorder that affects the cerebellum, the part of the brain responsible for coordinating voluntary movements. It is caused by mutations in the TTBK2 gene, which provides instructions for making a protein that helps regulate the formation and function of neurons.
SCA11 is inherited in an autosomal dominant pattern, which means that a person only needs to inherit one copy of the mutated gene from one parent to develop the condition. The age of onset for SCA11 ranges from the late teens to early adulthood, and symptoms can progress slowly over several decades.
Symptoms of SCA11
The symptoms of SCA11 can vary widely between individuals and may include:
- Unsteady gait and difficulty with coordination
- Tremors
- Difficulty with speech and swallowing
- Abnormal eye movements
- Numbness or tingling in the limbs
- Muscle weakness or stiffness
- Difficulty with fine motor skills, such as writing or buttoning clothes
As the disease progresses, individuals with SCA11 may experience more severe symptoms, such as cognitive decline, dementia, and depression.
Diagnosis of SCA11
Diagnosis of SCA11 typically involves a combination of clinical evaluation, genetic testing, and imaging studies.
A doctor may perform a physical exam to assess a patient’s coordination, reflexes, and muscle strength. They may also order imaging studies such as an MRI or CT scan to evaluate the structure of the brain and identify any abnormalities.
Genetic testing is the most definitive way to diagnose SCA11. A blood or saliva sample is typically collected and analyzed to look for mutations in the TTBK2 gene. This can be done using a variety of techniques, including next-generation sequencing (NGS) and Sanger sequencing.
NGS Genetic Test Cost for SCA11
The cost of an NGS Genetic Test for SCA11 in India can vary depending on the laboratory and the specific test being performed. However, on average, the cost of an NGS Genetic Test for SCA11 is around INR 20,000.
It is important to note that genetic testing may not be covered by insurance and may require out-of-pocket expenses. However, many laboratories offer financial assistance programs or payment plans to help make testing more accessible.
Conclusion
SCA11 is a rare but debilitating neurodegenerative disorder that can cause a wide range of symptoms. Genetic testing, including NGS, is the most definitive way to diagnose SCA11 and can help individuals and their families better understand their risk for the condition. If you or a loved one is experiencing symptoms of SCA11, it is important to speak with a healthcare professional and consider genetic testing.
At DNA Labs India, we offer a comprehensive range of genetic testing services, including NGS Genetic Testing for SCA11. Our team of experienced scientists and genetic counselors is committed to providing accurate, timely, and compassionate care to all of our patients. Contact us today to learn more about our services and how we can help you.
Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for TTBK2 Gene Spinocerebellar ataxia type 11, autosomal dominant NGS Genetic Test
| Test Name | TTBK2 Gene Spinocerebellar ataxia type 11, autosomal dominant NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card o |
| Test type | Neurologist |
| Pre-test Information | Clinical History of Patient who is going for TTBK2 Gene Spinocerebellar ataxia type 11, autosomal dominant NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with TTBK2 Gene Spinocerebellar ataxia type 11, autosomal dominant |
| Disease | Neurological Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for TTBK2 Gene Spinocerebellar ataxia type 11, autosomal dominant NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with TTBK2 Gene Spinocerebellar ataxia type 11, autosomal dominant |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for TTBK2 Gene Spinocerebellar ataxia type 11, autosomal dominant NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
