TUBG1 Gene Neurodevelopmental Malformation and Microcephaly: NGS Genetic Test
Neurodevelopmental malformations and microcephaly are two serious neurological conditions that can have a profound impact on a person’s life. They are caused by a variety of genetic and environmental factors, and diagnosing them can be challenging. However, advances in genetic testing have made it possible to identify the specific genes responsible for these conditions, including the TUBG1 gene.
The TUBG1 Gene and Neurodevelopmental Malformations
The TUBG1 gene is responsible for encoding a protein called gamma-tubulin, which is essential for the proper functioning of the microtubules that make up the cell’s cytoskeleton. Mutations in this gene have been linked to a variety of neurodevelopmental malformations, including microcephaly, lissencephaly, and agenesis of the corpus callosum.
Microcephaly is a condition in which the head circumference is smaller than normal, which can indicate a smaller brain size. This can lead to developmental delays, intellectual disability, and other neurological problems. Lissencephaly is a condition in which the surface of the brain is smooth, rather than having the normal folds and grooves. This can also lead to developmental delays and intellectual disability. Agenesis of the corpus callosum is a condition in which the band of nerve fibers connecting the two hemispheres of the brain fails to develop properly, which can also lead to developmental delays and intellectual disability.
NGS Genetic Test for TUBG1 Gene Mutations
If you or a loved one has symptoms of a neurodevelopmental malformation or microcephaly, it may be worth considering genetic testing to identify the underlying cause. The most effective type of genetic testing for these conditions is next-generation sequencing (NGS) of the TUBG1 gene.
NGS is a high-throughput method of DNA sequencing that can rapidly identify mutations in specific genes, including the TUBG1 gene. This test involves collecting a small sample of DNA, typically from a blood or saliva sample, and analyzing it for mutations in the TUBG1 gene.
Symptoms of Neurodevelopmental Malformations and Microcephaly
The symptoms of neurodevelopmental malformations and microcephaly can vary depending on the severity of the condition. Some common symptoms include:
- Small head size
- Developmental delays
- Intellectual disability
- Seizures
- Difficulty with motor skills
- Speech and language delays
- Behavioral problems
Diagnosing Neurodevelopmental Malformations and Microcephaly
Diagnosing neurodevelopmental malformations and microcephaly can be challenging, as there are many different conditions that can cause similar symptoms. However, genetic testing can help identify the specific genetic mutations responsible for these conditions.
If you or a loved one is experiencing symptoms of a neurodevelopmental malformation or microcephaly, it is important to talk to a healthcare provider about the possibility of genetic testing. Testing can help provide a more accurate diagnosis, which can lead to more effective treatment and management of symptoms.
Cost of NGS Genetic Test for TUBG1 Gene Mutations
The cost of an NGS Genetic Test for TUBG1 gene mutations can vary depending on the specific testing provider and location. However, the average cost in India is around INR 20,000.
Conclusion
Neurodevelopmental malformations and microcephaly can have a significant impact on a person’s life, but genetic testing can help identify the underlying cause and provide more effective treatment and management of symptoms. If you or a loved one is experiencing symptoms of these conditions, it may be worth considering an NGS Genetic Test for mutations in the TUBG1 gene.
Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for TUBG1 Gene Neurodevelopmental malformation and microcephaly NGS Genetic Test
| Test Name | TUBG1 Gene Neurodevelopmental malformation and microcephaly NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card o |
| Test type | Neurologist |
| Pre-test Information | Clinical History of Patient who is going for TUBG1 Gene Neurodevelopmental malformation and microcephaly NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with TUBG1 Gene Neurodevelopmental malformation and microcephaly |
| Disease | Neurological Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for TUBG1 Gene Neurodevelopmental malformation and microcephaly NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with TUBG1 Gene Neurodevelopmental malformation and microcephaly |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for TUBG1 Gene Neurodevelopmental malformation and microcephaly NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
