ZNF81 Gene and Mental Retardation, X-linked Type 45: Symptoms, Diagnosis, and NGS Genetic Test Cost
Mental retardation, also known as intellectual disability, is a condition characterized by significant limitations in cognitive functioning and adaptive behavior. It affects about 1-3% of the population worldwide and can be caused by a variety of genetic and environmental factors. One such genetic factor is the ZNF81 gene, which has been linked to X-linked mental retardation type 45 (MRX45). In this blog, we will discuss the symptoms, diagnosis, and NGS Genetic Test cost for MRX45.
Symptoms of MRX45
MRX45 is a rare genetic disorder that primarily affects males. It is caused by mutations in the ZNF81 gene, which provides instructions for making a protein that plays a role in the development and function of the brain. The symptoms of MRX45 can vary widely, but typically include:
- Moderate to severe intellectual disability
- Delayed speech and language development
- Behavioral problems, such as hyperactivity and aggression
- Seizures
- Abnormal facial features, such as a prominent forehead and a small chin
These symptoms can be present from birth or may become apparent during early childhood. MRX45 is a lifelong condition that requires ongoing support and care.
Diagnosis of MRX45
MRX45 is diagnosed through genetic testing, which can identify mutations in the ZNF81 gene. This testing can be done using a variety of methods, including:
- Next-generation sequencing (NGS)
- Sanger sequencing
- PCR-based testing
NGS is a powerful and efficient method for genetic testing that can identify a wide range of genetic mutations. It is particularly useful for rare genetic disorders like MRX45.
NGS Genetic Test Cost for MRX45
The cost of NGS Genetic Testing for MRX45 can vary depending on the specific test and the laboratory performing the testing. In India, the cost of NGS Genetic Testing for MRX45 is typically around INR 20,000.
It is important to note that genetic testing for MRX45 may not be covered by insurance and can be expensive. However, early diagnosis and intervention can improve outcomes for individuals with MRX45, making genetic testing an important tool for families affected by this condition.
Conclusion
MRX45 is a rare genetic disorder that can cause significant intellectual disability and other symptoms. Genetic testing, including NGS, can help diagnose this condition and provide important information for families affected by MRX45. While the cost of genetic testing for MRX45 can be high, early diagnosis and intervention can improve outcomes for individuals with this condition.
If you suspect that you or a family member may have MRX45, talk to your doctor about genetic testing options and the potential benefits and risks of testing.
Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for ZNF81 Gene Mental retardation, X-linked type 45 NGS Genetic Test
| Test Name | ZNF81 Gene Mental retardation, X-linked type 45 NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card o |
| Test type | Neurologist |
| Pre-test Information | Clinical History of Patient who is going for ZNF81 Gene Mental retardation, X-linked type 45 NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with ZNF81 Gene Mental retardation, X-linked type 45 |
| Disease | Neurological Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for ZNF81 Gene Mental retardation, X-linked type 45 NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with ZNF81 Gene Mental retardation, X-linked type 45 |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for ZNF81 Gene Mental retardation, X-linked type 45 NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
