HTRA2 Gene PARK13 Parkinson NGS Genetic Test: Cost, Symptoms, Diagnosis
Parkinson’s disease is a neurodegenerative disorder that affects millions of people worldwide. It is a chronic and progressive disorder that affects movement and causes tremors, stiffness, and difficulty in balance and coordination. While the exact cause of Parkinson’s disease is still unknown, recent research has identified a potential genetic link. One of the genes that have been found to be linked to Parkinson’s disease is the HTRA2 gene, also known as PARK13.
What is the HTRA2 Gene?
The HTRA2 gene is responsible for producing a protein known as high-temperature requirement protein A2. This protein plays a crucial role in the mitochondria, which are the powerhouses of the cells. The protein is involved in the regulation of the mitochondria’s function and helps in maintaining their structural integrity. When the HTRA2 gene is mutated, it can lead to a decrease in the protein’s production, which can result in mitochondrial dysfunction. Mitochondrial dysfunction has been linked to several neurodegenerative disorders, including Parkinson’s disease.
How is the HTRA2 Gene Linked to Parkinson’s Disease?
Research has found that mutations in the HTRA2 gene are associated with an increased risk of developing Parkinson’s disease. This gene’s mutations can cause a decrease in the production of the high-temperature requirement protein A2, which can lead to mitochondrial dysfunction. Mitochondrial dysfunction has been linked to the death of dopamine-producing neurons, which are essential for the regulation of movement. The death of these neurons can result in the development of Parkinson’s disease symptoms.
NGS Genetic Test for HTRA2 Gene PARK13 Parkinson
The NGS Genetic Test for the HTRA2 gene PARK13 Parkinson is a genetic test that can determine if an individual has a mutation in the HTRA2 gene. This test uses next-generation sequencing (NGS) technology to analyze an individual’s DNA for mutations in the HTRA2 gene. The test is highly accurate and can detect even minor mutations in the gene.
Cost of the NGS Genetic Test for HTRA2 Gene PARK13 Parkinson
The cost of the NGS Genetic Test for the HTRA2 gene PARK13 Parkinson in India is approximately INR 20,000. The cost may vary depending on the testing facility and the location.
Symptoms of Parkinson’s Disease
The symptoms of Parkinson’s disease can vary from person to person and may include:
- Tremors or shaking
- Stiffness in the limbs and torso
- Difficulty in balance and coordination
- Slow movement or bradykinesia
- Difficulty in initiating movement or akinesia
- Impaired posture and balance
Diagnosis of Parkinson’s Disease
Diagnosing Parkinson’s disease can be challenging as there is no definitive test for the disease. The diagnosis is usually made based on the individual’s medical history, physical examination, and the presence of Parkinson’s disease symptoms. In some cases, a doctor may order imaging tests or blood tests to rule out other conditions that may be causing the symptoms. Genetic testing may also be recommended for individuals with a family history of Parkinson’s disease or those with early-onset Parkinson’s disease.
Conclusion
The NGS Genetic Test for the HTRA2 gene PARK13 Parkinson can help identify individuals at risk of developing Parkinson’s disease. Early diagnosis and treatment can help manage the symptoms of Parkinson’s disease and improve the individual’s quality of life. If you are experiencing Parkinson’s disease symptoms or have a family history of the disease, talk to your doctor about the NGS Genetic Test for the HTRA2 gene PARK13 Parkinson.
| Test Name | HTRA2 Gene PARK13 Parkinson NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card o |
| Test type | Neurologist |
| Pre-test Information | Clinical History of Patient who is going for HTRA2 Gene PARK13 Parkinson NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with HTRA2 Gene PARK13 Parkinson |
| Disease | Neurological Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for HTRA2 Gene PARK13 Parkinson NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with HTRA2 Gene PARK13 Parkinson |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for HTRA2 Gene PARK13 Parkinson NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
