HLA – NARCOLEPSY (DRB1*15 DQB1*06:02 DQA1*01:02) Test: Symptoms, Diagnosis, and Cost
Narcolepsy is a neurological disorder that affects the ability to regulate sleep-wake cycles. It is characterized by excessive daytime sleepiness, sudden loss of muscle tone (cataplexy), hallucinations, and sleep paralysis. Narcolepsy usually begins in adolescence or early adulthood and can have a significant impact on a person’s quality of life.
HLA – Narcolepsy Test
The HLA – narcolepsy test is a genetic test that helps diagnose narcolepsy. It looks for specific variations in the human leukocyte antigen (HLA) genes that are associated with narcolepsy. The test analyzes three genes: DRB1*15, DQB1*06:02, and DQA1*01:02. These genes are found on chromosome 6 and are involved in the body’s immune response.
Symptoms of Narcolepsy
The symptoms of narcolepsy can vary from person to person, but the most common symptoms include:
- Excessive daytime sleepiness
- Cataplexy (sudden loss of muscle tone)
- Hallucinations
- Sleep paralysis
- Disrupted nighttime sleep
- Automatic behavior (performing routine tasks without conscious awareness)
These symptoms can significantly impact a person’s daily life, making it difficult to perform daily tasks, maintain relationships, and hold down a job.
Diagnosing Narcolepsy
Diagnosing narcolepsy can be challenging because the symptoms are similar to other sleep disorders. A sleep specialist will typically perform a physical exam and ask about the patient’s symptoms, medical history, and sleep habits. They may also order a sleep study, which involves monitoring the patient’s brain waves, heart rate, breathing, and muscle activity while they sleep.
The HLA – narcolepsy test can also be used to help diagnose narcolepsy. If the test comes back positive for the DRB1*15, DQB1*06:02, and DQA1*01:02 genes, it is an indication that the person may be at a higher risk for developing narcolepsy.
Cost of HLA – Narcolepsy Test
The cost of the HLA – narcolepsy test in India is typically around INR 8500. However, the cost may vary depending on the laboratory and location.
Conclusion
Narcolepsy is a challenging disorder that can significantly impact a person’s daily life. The HLA – narcolepsy test is a useful tool for diagnosing narcolepsy and can help patients get the treatment they need to manage their symptoms. If you’re experiencing symptoms of narcolepsy, talk to your doctor about whether the HLA – narcolepsy test is right for you.
At DNA Labs India, we offer a wide range of genetic tests, including the HLA – narcolepsy test. Our team of experts is committed to providing accurate and reliable results to help our patients make informed decisions about their health. Contact us today to learn more about our genetic testing services.
Narcolepsy is a multigenic environmentally influenced neurologic sleep disorder affecting 0.01 to 0.15% of the population. Among other genetic regions, it is associated with the HLA class II region of the HLA complex. HLA-DQ6 and/or HLA-DR15 confer susceptibility to Narcolepsy, with variable relative risk according to ethnicity.
Test Name | HLA – Narcolepsy (DRB115 DQB106:02 DQA1*01:02) Test |
---|---|
Sample type | 4 mL (3 mL min.) whole blood in 1 Lavender Top (EDTA) tube OR 6 mL (3 mL min.) whole blood in 1 Yellow Top (ACD) tube. Ship refrigerated. DO NOT FREEZE. |
Test type | Physician, Neurologist |
Pre-test Information | No special preparation required |
Disease | Disease Association |
Method | Sequencing Based Typing (SBT) |
Purpose | NULL |
Preparation | Room Temperature: NA, Refrigerator:96 hrs, Frozen: NA |
Fasting | No special preparation required |
Get Reports | 10-12 days |
Test Price | INR ₹ 8500 |
Note: We offer free home sample collection for online bookings for HLA – Narcolepsy (DRB115 DQB106:02 DQA1*01:02) Test and the test costs a special discounted price of 8500 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.