Introduction Lynch syndrome, also known as Hereditary Non-Polyposis Colorectal Cancer (HNPCC), is the most common form of hereditary colorectal cancer. It is an inherited condition that significantly increases a person’s risk of developing certain cancers, often at a younger age than sporadic (non-hereditary) cases. Understanding this condition is the first step toward proactive health management […]
Down syndrome, also known as Trisomy 21, is the most common chromosomal condition diagnosed in India and worldwide . It is a genetic disorder caused by the presence of an extra copy of chromosome 21, which affects a person’s physical and cognitive development. This comprehensive guide provides detailed clinical information about Down syndrome, including its […]
India has made significant progress in food availability, agricultural production, and access to nutrition programmes. Yet, the country’s nutrition story remains complex. A full plate does not always mean a nutritionally complete plate. Many Indians may consume enough calories while still falling short of essential vitamins and minerals. This phenomenon—often described as hidden hunger or […]
Facioscapulohumeral muscular dystrophy (FSHD) is one of the most prevalent muscular dystrophies, yet it remains widely underdiagnosed, particularly in India . Characterized by progressive muscle weakness, it primarily affects the face, shoulders, and upper arms. For the Indian population, understanding this condition is the first critical step toward timely diagnosis and management. What is Facioscapulohumeral […]
Understanding Macular Atrophy: Beyond the Basics of Vision Loss Macular atrophy represents a significant challenge in eye health, characterized by the progressive and irreversible loss of cells in the macula—the central part of the retina responsible for sharp, detailed vision. As an advanced form of age-related macular degeneration (AMD), it leads to permanent impairment of […]
World Sjögren’s Day 2026 is observed on July 23, providing an opportunity to raise awareness about a frequently overlooked autoimmune condition that can affect more than just the eyes and mouth. While persistent dry eyes and dry mouth are its best-known symptoms, Sjögren’s disease may also involve the joints, skin, lungs, kidneys, nervous system and […]
Understanding the CRISPR Revolution Imagine having the ability to edit the fundamental code of life—the DNA that dictates everything from our eye color to our susceptibility to disease. This is not science fiction. It is the reality of CRISPR-Cas gene editing, a groundbreaking technology that has transformed the landscape of genetics and medicine. CRISPR, an […]
Understanding India’s First Approved Vaccine, Qdenga For decades, dengue has been a formidable public health challenge in India, with the country accounting for nearly one-third of the global dengue burden . The monsoon seasons often bring a surge in cases, overwhelming hospitals and causing significant morbidity and mortality. In a landmark development, India’s drug regulator, […]
Parkinson’s disease (PD) has long been characterized as a neurodegenerative disorder with an unknown cause in the vast majority of cases. However, this clinical paradigm is shifting rapidly. Recent research reveals that genetics play a far more significant role in Parkinson’s disease than previously understood, with studies suggesting that up to 15-20% of early-onset cases […]
Polycystic Ovary Syndrome (PCOS) is one of the most common hormonal disorders affecting women of reproductive age, with an estimated prevalence of 8–13% globally and increasing recognition in India. While PCOS is often associated with irregular menstrual cycles, infertility, acne, and weight gain, research has revealed another important concern—its impact on long-term cardiovascular health. Several […]
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