CDH1 Gene Gastric Cancer: Symptoms, Diagnosis, and NGS Genetic Test Cost
Gastric cancer, also known as stomach cancer, is a type of cancer that develops in the lining of the stomach. It is the fifth most common cancer worldwide and the third leading cause of cancer-related deaths. In India, it is estimated that more than 50,000 new cases of gastric cancer are diagnosed each year.
While the exact cause of gastric cancer is not known, certain genetic mutations can increase the risk of developing this cancer. One such gene is the CDH1 gene, which is associated with hereditary diffuse gastric cancer (HDGC).
CDH1 Gene and HDGC
The CDH1 gene provides instructions for making a protein called E-cadherin, which is involved in the adhesion of cells. Mutations in this gene can lead to a decrease or loss of E-cadherin, which can cause cells in the stomach to become disorganized and grow uncontrollably, leading to gastric cancer.
HDGC is a rare inherited form of gastric cancer that is caused by mutations in the CDH1 gene. Individuals with HDGC have a high risk of developing gastric cancer, with a lifetime risk of up to 80% for men and 70% for women.
Symptoms of Gastric Cancer
Gastric cancer often does not cause any symptoms in its early stages. However, as the cancer grows, it can cause a range of symptoms, including:
- Abdominal pain or discomfort
- Loss of appetite
- Nausea and vomiting
- Feeling full after eating small amounts of food
- Bloating
- Difficulty swallowing
- Unexplained weight loss
- Fatigue
If you experience any of these symptoms, it is important to see a doctor for an evaluation.
Diagnosis of Gastric Cancer
Diagnosing gastric cancer typically involves a combination of tests, including:
- Physical exam and medical history
- Blood tests
- Endoscopy
- Biopsy
- Imaging tests, such as CT scan or MRI
If gastric cancer is diagnosed, further testing may be needed to determine the stage of the cancer and the best treatment plan.
NGS Genetic Test for HDGC
If you have a family history of gastric cancer, particularly if multiple family members have been affected, you may be at risk for HDGC. In this case, genetic testing can be helpful in identifying whether you have a CDH1 gene mutation.
NGS (next-generation sequencing) Genetic Testing is a type of genetic testing that can analyze multiple genes at once, including the CDH1 gene. This test can help identify individuals who are at risk for HDGC and allow for early intervention and prevention.
Cost of NGS Genetic Test in India
The cost of NGS Genetic Testing for HDGC in India can vary depending on the provider and the specific test ordered. However, on average, the cost of this test is around INR 20,000.
While this may seem like a significant expense, early detection and intervention can help prevent or reduce the impact of gastric cancer, potentially saving both lives and healthcare costs in the long run.
Conclusion
Gastric cancer is a serious disease that can be caused by genetic mutations, including mutations in the CDH1 gene. If you have a family history of gastric cancer, it is important to be aware of your risk and to seek medical attention if you experience any symptoms.
NGS Genetic Testing can be a helpful tool in identifying individuals at risk for HDGC and allowing for early intervention and prevention. While the cost of this testing may seem high, it can potentially save lives and healthcare costs in the long run.
For more information on gastric cancer, HDGC, and genetic testing, contact DNA Labs India today.
| Test Name | CDH1 Gene Gastric cancer, hereditary diffuse NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | Oncologist |
| Pre-test Information | Clinical History of Patient who is going for CDH1 Gene Gastric cancer, hereditary diffuse NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with CDH1 Gene Gastric cancer, hereditary diffuse NGS Genetic Test gene CDH1 |
| Disease | Cancer |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for CDH1 Gene Gastric cancer, hereditary diffuse NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with CDH1 Gene Gastric cancer, hereditary diffuse NGS Genetic Test gene CDH1 |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for CDH1 Gene Gastric cancer, hereditary diffuse NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
