DNA Genetic Methylation Testing: Decoding Your Epigenetic Blueprint for Health and Longevity
DNA methylation testing has emerged as a revolutionary tool in personalized medicine, offering insights into how lifestyle, environment, and genetics intersect to influence aging and disease risk. At DNA Labs India, our advanced DNA Genetic Methylation Test (priced at ₹18,000, discounted from ₹25,000) delivers a comprehensive analysis of your epigenetic profile, empowering you to take proactive steps toward optimizing healthspan and longevity. Results are delivered in just 10 days, with free sample collection across India.**
What Does the DNA Genetic Methylation Test Reveal?
Biological Age vs. Chronological Age
Your biological age reflects how well your cells and organs are functioning compared to your calendar age. By analyzing methylation patterns at key genomic sites (such as ELOVL2, FHL2), the test calculates your epigenetic clock – a scientifically validated measure of aging. Accelerated biological age may indicate higher risks for age-related conditions like diabetes, cardiovascular disease, or neurodegenerative disorders.
Methylation Pathway Efficiency
The test evaluates critical biochemical pathways:
- Folate and Methionine Cycles: Identifies bottlenecks in SAMe (S-adenosylmethionine) production, the body’s primary methyl donor.
- Transsulfuration Pathway: Assesses glutathione synthesis, crucial for detoxification and antioxidant defense.
- Neurotransmitter Regulation: Analyzes COMT gene variants affecting dopamine and estrogen metabolism.
Disease Risk Profiling
Abnormal methylation is linked to:
- Cancer: Silencing of tumor suppressor genes (for example, MGMT promoter methylation in glioblastoma).
- Cardiovascular Health: Elevated homocysteine levels due to MTHFR gene mutations.
- Autoimmune Disorders: Dysregulation of immune-related genes like HLA-DRB1.
Nutrient Requirements
The report highlights deficiencies in:
- Methylation donors: Folate (B9), B12, betaine, and choline.
- Cofactors: Zinc, magnesium, and SAMe precursors.
Longevity Markers
Identifies epigenetic signatures associated with healthspan extension, such as:
- SIRT1 (linked to calorie restriction benefits).
- FOXO3 (associated with exceptional longevity).
Interpreting Your Test Report: What to Expect
Methylation Pathway Map
A visual flowchart color-codes metabolic bottlenecks:
- Red: Significant impairment (such as MTHFR C677T mutation reducing folate metabolism).
- Amber: Moderate dysfunction (such as heterozygous CBS gene variant).
- Green: Optimal function.
Genotype Analysis
Key genes tested include:
- MTHFR (rs1801133, rs1801131): Folate metabolism.
- COMT (rs4680): Neurotransmitter breakdown.
- GSTP1 (rs1695): Detoxification capacity.
- APOE (rs429358, rs7412): Lipid metabolism and Alzheimer’s risk.
Biomarker Quantification
- SAM/SAH Ratio: A low ratio indicates methyl donor deficiency.
- Glutathione Levels: Suboptimal levels impair detoxification.
Personalized Recommendations
- Diet: Tailored plans for methyl-rich foods (leafy greens, eggs) or avoidance of processed meats.
- Supplements: Active folate (5-MTHF), methylcobalamin (B12), or betaine based on genetic variants.
- Lifestyle: Stress-reduction techniques (yoga, meditation) to lower cortisol-induced methylation imbalances.
Why Choose DNA Labs India?
Cutting-Edge Technology
- Next-Generation Sequencing (NGS): Analyzes hundreds of CpG islands with high accuracy.
- Methylation-Specific PCR: Detects promoter methylation in cancer-related genes like BRCA1 and MLH1.
Fast, Transparent Reporting
- 10-Day Turnaround: Quick results via secure portal.
- Raw Data Access: Download FASTQ/VCF files for further analysis.
Expert Support
- Genetic Counseling: Post-report consultation to explain findings.
- Actionable Plans: Integrate results with Ayurvedic or functional medicine protocols.
Affordable Pricing
- ₹18,000 (Discounted from ₹25,000): Includes free home sample collection in over a hundred cities.
Conclusion: Take Control of Your Epigenetic Destiny
DNA Labs India’s DNA Genetic Methylation Test is more than a diagnostic tool – it’s a roadmap to healthier aging. By understanding your unique epigenetic profile, you can:
- Reverse biological age through targeted interventions.
- Mitigate risks for cancer, dementia, and metabolic disorders.
- Optimize nutrition and lifestyle for longevity.
Act Now: Book your test at ₹18,000 (limited-time offer) and receive results within 10 days. Visit DNA Labs India or call 07941057551 to schedule free sample collection.
For more information about MGMT Methylation Assay, contact DNA Labs India.
Test Name | DNA Genetic Methylation Test |
---|---|
Sample type | Blood |
Test type | Genetic |
Pre-test Information | The Methylation Panel stands as a groundbreaking test crafted to provide understanding of the pivotal biochemical methylation pathway. Plasma measurement of methylation metabolites and the analysis of genetic single nucleotide polymorphisms (SNPs) via buccal swab form the core of this assessment. Patient outcomes are summarized on a user-friendly Interpretation-at-a-Glance (IAAG) graphic on the front page for swift evaluation of methylation status. Furthermore, the report includes a methylation pathway graphic to offer a lucid comprehension of the underlying biochemistry. |
Disease | Genetics |
Method | MLPA |
Purpose | The Methylation Panel from DNA Labs India integrates both phenotypic and genotypic data into a single profile. It simplifies intricate biochemistry using easily understandable graphics. This comprehensive assessment covers methylation and transsulfuration markers, along with numerous genetic SNPs, offering a thorough evaluation unparalleled in methylation assessment. |
Preparation | Ambient |
Fasting | No need |
Get Reports | 15-20 days |
Test Price | ₹ 18000 INR |
Note: We offer free home sample collection for online bookings for MGMT Methylation Panel and the test costs a special discounted price of 60000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.