PDGFRA Gene: Selective Sequencing of Exons 12, 14, and 18 NGS Genetic Test
PDGFRA (Platelet-Derived Growth Factor Receptor Alpha) gene is responsible for encoding a receptor protein that plays a crucial role in the regulation of cell growth and development. Mutations in the PDGFRA gene are associated with various diseases, including gastrointestinal stromal tumors (GISTs), chronic eosinophilic leukemia, and systemic mastocytosis.
Why is Selective Sequencing of Exons 12, 14, and 18 Important?
Selective sequencing of exons 12, 14, and 18 of the PDGFRA gene is important because it helps to identify specific mutations that are associated with GISTs. GISTs are a type of tumor that occurs in the gastrointestinal tract and are often resistant to traditional chemotherapy and radiation treatments.
By identifying specific mutations in the PDGFRA gene, doctors can develop personalized treatment plans that target the specific mutations present in the patient’s tumor. This approach has been shown to be more effective than traditional chemotherapy and radiation treatments.
NGS Genetic Test
The NGS (Next-Generation Sequencing) Genetic Test is a cutting-edge technology that allows for the rapid and accurate sequencing of large portions of the genome. This test is used to identify mutations in the PDGFRA gene and other genes that are associated with various diseases.
The NGS Genetic Test is a non-invasive test that involves collecting a small sample of blood or tissue from the patient. The sample is then sent to a laboratory where it is analyzed using advanced sequencing technologies. The results of the test are typically available within a few weeks.
Symptoms and Diagnosis
The symptoms of GISTs can vary depending on the location of the tumor. Common symptoms include abdominal pain, nausea, vomiting, and blood in the stool. GISTs can be difficult to diagnose, and many patients are not diagnosed until the tumor has grown large enough to cause symptoms.
If a GIST is suspected, doctors may perform a variety of tests, including imaging tests such as CT scans and MRIs, as well as biopsies to confirm the diagnosis. Once the diagnosis is confirmed, doctors may recommend selective sequencing of exons 12, 14, and 18 of the PDGFRA gene to identify specific mutations.
Cost of Selective Sequencing of Exons 12, 14, and 18 NGS Genetic Test
The cost of selective sequencing of exons 12, 14, and 18 of the PDGFRA gene using the NGS Genetic Test varies depending on the laboratory and location. In India, the cost of this test typically ranges from INR 20,000 to INR 30,000.
Conclusion
The selective sequencing of exons 12, 14, and 18 of the PDGFRA gene using the NGS Genetic Test is an important diagnostic tool for identifying specific mutations associated with GISTs. This information can be used to develop personalized treatment plans that target the specific mutations present in the patient’s tumor, leading to more effective outcomes. The cost of this test varies depending on the laboratory and location, but it is a worthwhile investment for patients with suspected GISTs.
At DNA Labs India, we offer cutting-edge NGS Genetic Test services to help diagnose and treat various diseases. Contact us today to learn more about our services and how we can help you.
| Test Name | PDGFRA Gene PDGFRA, selective sequencing of exons 12, 14 and 18 NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | Oncologist |
| Pre-test Information | Clinical History of Patient who is going for PDGFRA Gene PDGFRA, selective sequencing of exons 12, 14 and 18 NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with PDGFRA Gene PDGFRA, selective sequencing of exons 12, 14 and 18 NGS Genetic Test gene PDGFRA |
| Disease | Cancer |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for PDGFRA Gene PDGFRA, selective sequencing of exons 12, 14 and 18 NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with PDGFRA Gene PDGFRA, selective sequencing of exons 12, 14 and 18 NGS Genetic Test gene PDGFRA |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for PDGFRA Gene PDGFRA, selective sequencing of exons 12, 14 and 18 NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
