DNA Labs India NIPT or Non-Invasive Prenatal test is performed, analyzed and supported by DNA Labs India’s team of highly experienced laboratory scientists and genetic clinicians at an affordable cost. DNA Labs India is ranked as India’s Most Trusted NIPT Testing facility by doctors and hospitals across India.
DNA Labs India is an expert in genetic testing and a global leader in the diagnosis of rare genetic diseases. We conform to the highest standards for diagnostic testing and reporting.
The Non-Invasive Prenatal Testing (NIPT) Test Details:
NIPT screens for the three most common trisomy conditions present at birth which are:
- Down Syndrome
- Edwards Syndrome
- Patau Syndrome.
Independent validation studies, including the worlds largest study on the use of NIPT in clinical practice in nearly 147,000 women, have shown NIPT has an accuracy rate of over 99.99% for detection of these above conditions.
THE TEST CAN ALSO DETECT ABNORMALITIES OF THE SEX CHROMOSOMES:
- Turner syndrome (Monosomy X)
- Klinefelter syndrome (XXY)
- Jacobs syndrome (XYY)
- Triple X syndrome (XXX)
List of NIPT Tests
How does NIPT non-invasive prenatal testing work?
Small amounts of a baby’s DNA pass into the bloodstream of the mother during pregnancy. Cell-free DNA fragments (cfDNA) are short fragments of DNA, which can be found circulating in the mother blood. During pregnancy, cfDNA fragments originating from both the mother and fetus are present in the maternal blood circulation.
New technology allows us to analyze this DNA directly from the mother’s blood and screen for chromosomal abnormalities. The NIPT test requires taking a small maternal blood sample. cfDNA in the maternal blood is then analysed with our proprietary genetic sequencing technology and bioinformatics pipelines to screen for any chromosomal abnormality in the fetus. If any abnormality is present, small excesses or deficits in counts of the affected chromosome can be detected.
Until recently, it has only been possible to screen for abnormalities with highly invasive procedures such as chorionic villus sampling (CVS) or amniocentesis. These tests carry an elevated risk of miscarriage and are only performed later in pregnancy.
Initial screening with NIPT can help to avoid this potentially unnecessary and invasive testing. There is no risk to mother or baby, and NIPT test provides the earliest testing available.
The technology behind the NIFTY test allows for highly accurate results with detection rates for the three most common trisomy conditions present at birth (Down Syndrome, Edwards Syndrome and Patau Syndrome) of over 99%. But its important to understand that non-invasive prenatal tests such NIPT are classified as screening tests. This means that they do not test with 100% accuracy, such as with an invasive diagnostic procedure such as amniocentesis.
What is NIPT testing?
Our DNA carries all the genetic information we require for normal health and development. It exists in our cells as 23 pairs of chromosomes. During pregnancy, chromosomal abnormalities can arise in the developing baby as a result of incorrect egg or sperm formation, or during the earliest stages of the baby’s development. These chromosomal abnormalities can significantly affect the health and well-being of a baby and it is important to identify any abnormalities as early as possible.
NIPT Test delivers a clear positive or negative result for chromosomal abnormalities, where an extra copy of one chromosome is present (Trisomy). Down syndrome, the most common chromosomal abnormality can be detected with an accuracy rate of >99,9%.
When do doctors recommend NIPT test?
- Maternal age 35 years or older at delivery
- Contraindications for invasive prenatal testing, such as placenta prevaria, risk of miscarriage, HBV infection etc.
- History of a prior pregnancy with a chromosomal abnormality
- Fetal ultrasonographic findings indicating an increased risk of T21, T18 or T13
- Requires reassurance following previous screening result
- Received IVF Treatment or has previously suffered from habitual abortion
What is The NIFTY Non-Invasive Prenatal Testing (NIPT) Test?
The NIFTY Non-Invasive Prenatal Testing (NIPT) Test is a medical speciality that determines the cause and nature of diseases by examining and testing body tissues (10 ML in Streck tube). It is a The NIFTY Non-Invasive Prenatal Testing (NIPT) Test that screens for serious conditions.
NIPT test for Down syndrome :
The most common, well-known genetic abnormality is Down syndrome, caused by the presence of a third copy of chromosome 21. Approximately 22 in 10,000 babies are born with Down syndrome. It is associated with delayed physical development, typical facial features and mild to moderate intellectual disability.
NIPT Test for Edwards syndrome :
Edwards syndrome, also known as trisomy 18, is caused by an additional copy of chromosome 18. Edwards syndrome occurs in around one in every 6,000 pregnancies. Babies with this syndrome rarely survive due to abnormalities of the heart, kidneys and other internal organs.
NIPT Test for Patau syndrome :
Patau syndrome, also known as trisomy 13, is caused by an additional copy of chromosome 13. Like babies with trisomy 18, babies with trisomy 13 also have multiple birth defects and often don’t survive the first few months.
What type of sample are needed to do a The Non-Invasive Prenatal Testing (NIPT) Test?
A 10 ML in Streck tube for testing can be obtained from several bodily sources. The cells are the most commonly tested are derived.
Standard Biological The NIFTY Non-Invasive Prenatal Testing (NIPT) Test Samples: 10 ML in Streck tube
How accurate is the Non-Invasive Prenatal Testing (NIPT) Test?
The Non-Invasive Prenatal Testing (NIPT) Test is generally considered to be the most accurate testing method available. DNA Labs India’s NIPT Test is considered as a benchmark by most doctors at the best cost. Our NIPT test is the most precise and accurate that is available at the best cost in India.
The results will show whether any of the described chromosomal abnormalities have been detected in your baby. If the results are normal, this will provide you with the reassurance that these most common genetic abnormalities are not present.
If the NIPT is positive for a chromosomal abnormality, your physician will offer you additional testing for confirmation of test results and refer you for genetic counselling to discuss the implications and choices available for you and your baby
How many days does it take to obtain Non-Invasive Prenatal Testing (NIPT) test results?
For a standard The Non-Invasive Prenatal Testing (NIPT) Test, DNA Labs India returns The NIFTY Non-Invasive Prenatal Testing (NIPT) test results in 7 to 10 business days once all samples are received at the lab.
DNA Labs India understands that waiting for The Non-Invasive Prenatal Testing (NIPT) Test results for this potentially life-changing test is stressful, so we provide speedy service without sacrificing accuracy.
Once complete, results are posted immediately to our secure online portal, and you will be notified by email right away.
How much does a Non-Invasive Prenatal Testing (NIPT) Test cost?
A standard The Non-Invasive Prenatal Testing (NIPT) Test cost you 12000/- to 13000/- INR.
Why Choose DNA Labs India for Non-Invasive Prenatal Testing (NIPT) Test?
DNA labs India’s Non-Invasive Prenatal Testing (NIPT) Test follows with dual testing for 100% accuracy when determining a Non-Invasive Prenatal Testing (NIPT) Test.
- We are the leading lab for Non-Invasive Prenatal Testing (NIPT) Test in India
- Greater Accuracy
- Collection centres across India
- Outstanding customer service
- Strict privacy and confidentiality assured
- Full-service laboratories providing testing for use in complex cases
What is Different between Illumina and Ion torrent NIPT Testing?
The clinical performance of two massively parallel shotgun sequencing (MPSS) NIPT methods using either an optical NGS technology (Illumina) or a semiconductor NGS technology (Iontorrent ThermoFisher) in high risk and in baseline risk pregnancies for the detection of trisomies 21, 18, 13, and monosomy X.
It appears clear from most clinical studies that, for the detection of any of the three main trisomies (T13, T18, and T21), the two index tests do not differ (upper 99% confidence interval limit of the difference) by more than 2.6% in clinical sensitivity, 0.64% in clinical specificity, 0.64% in FPR, and 0.65% in ACC. In terms of PPV and NPV, in high-risk pregnancies, index tests differed by less than 6.41% for PPV and 0.33% for NPV. In pregnancies with baseline risk, only the NPV could be reliably estimated and it did not differ (upper 99% confidence interval limit of the difference) by more than 0.33% between the two index tests.
How to Schedule an Appointment for The NIFTY Non-Invasive Prenatal Testing (NIPT) Test?
You can either book online at the link provided. If you book and make the payment home collection service is provided to patients of all The NIFTY Non-Invasive Prenatal Testing NIPT Test free of cost.
How can I locate a The NIFTY Non-Invasive Prenatal Testing (NIPT) Test facility?
DNA labs India has 3000 plus sample collection centres across India for The NIFTY Non-Invasive Prenatal Testing (NIPT) Test.
You can choose the centre and book The NIFTY Non-Invasive Prenatal Testing (NIPT) Test online. For all online bookings made and payment paid a home sample collection service is provided free of cost for NIPT Test.
List of The NIFTY Non-Invasive Prenatal Testing (NIPT) Test collection centres in India are Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Visakhapatnam, Kanpur, Nagpur, Lucknow, Thane, Bhopal, Indore, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivli, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi, Mumbai, Allahabad, Howrah, Ranchi, Gwalior, Jabalpur, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Chandigarh, Guntur, Guwahati, Solapur, Hubli–Dharwad, Mysore, Tiruchirappalli, Bareilly, Moradabad, Tiruppur, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal, Jalgaon, Kota, Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore, Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola