HLA Typing Test for Transplant
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Human leukocyte antigen (HLA) typing is a method to determine how closely the tissues of a transplant recipient match the tissues of their potential donor. Human leukocyte antigen (HLA) typing is used to match patients and donors for bone marrow or cord blood transplants. HLA are proteins, or markers, found on most cells in your body. HLA typing is a medical test used to assess whether organ and blood marrow donors are suitably and safely matched to a transplant recipient.
HLA testing is used to match organ and tissue transplant recipients with compatible donors. Different kinds of transplants require different levels of matching between donors and recipients. Human leukocyte antigen (HLA) typing is a method to determine how closely the tissues of a transplant recipient match the tissues of their potential donor. HLA typing is a medical test used to assess whether organ and blood marrow donors are suitably and safely matched to a transplant recipient.
The HLA match is the number of HLA markers that any two people have in common. HLA matching is usually based on either eight or 10 HLA markers. The more markers two people share, the better the match. When two individuals share the same HLA markers, they are said to be a good match.
The most likely place to find an HLA match between two people is among siblings who have the same mother and father. If two siblings inherit the very same HLA markers from both parents, they are said to be an HLA-identical match.
Two unrelated people can just happen to be a good HLA match, too. Although it is less likely, it is possible that you could have some of the same HLA markers as someone you don’t even know.
When will do HLA typing?
When a doctor decides that a bone marrow transplant is the best treatment for a patient, the patient, all of his or her siblings if they agree, and sometimes their parents will have samples collected for HLA typing. If one of the family members is an HLA-identical match, the lab will do further testing to be absolutely sure that they are the best match possible.
How Are HLA Genes Inherited?
Biological parents always share half of their HLA proteins with their children. This is also called a “half match.” Conversely, a child always is a half match with their parents. A child would share half of the colours on his cells with each of his parents. Siblings who share both parents are most likely to be an identical HLA match. Such siblings have a 1 in 4 chance of being a perfect HLA match (with perfectly matching coloured strings).
Because the HLA genes are located close together on your DNA, they are usually inherited as a group you inherit a whole set of colours not just one individual colour at a time. Your HLA type is composed of the set of HLA genes you inherited from your mother and the HLA genes you inherited from your father. In our analogy, the HLA genes contain information about the "colour of the strings" your cells will have.
Where will do HLA typing test in India?
DNA Labs India is a leading molecular diagnostic company dedicated to making a difference in patients’ lives through the discovery and commercialization of transformative tests to assess a person’s risk of developing the disease, guide treatment decisions and assess the risk of disease progression and recurrence.
HLA typing test cost in India
The cost of the HLA Typing Test for a single person (either donor or recipient) is 8000/-
How can I book my HLA typing test in India?
Visit the website www.dnalabsindia.com, for any DNA test. We can help you get your DNA test done. We have services in over 180 cities in India. Call us at the below-mentioned no.s or visit our sample collection centre nearby your location.
New Delhi: (011) 40849842
Mumbai : (022) 48937160
Kolkata : (033) 40836441
Chennai : (044) 48137110
Bangalore : (080) 45684079
Hyderabad : (040) 49171772
Ahmedabad : (079) 49107674