Heart failure with preserved ejection fraction may be driven primarily by dysfunctional visceral fat and harmful adipokinesâshifting screening toward waistâtoâheight ratio and treatment toward fatâtargeting therapies, including GLPâ1 agents. ⨠Whatâs new đ§ Fat biology over pressure đ§ Whoâs at risk (beyond BMI) đ Treatment implications đ How to measure (simple and scalable) 𧪠Why […]
Genetic testing of IVF embryos can help women aged 35â42 conceive in fewer transfers and may raise cumulative live birth rates, easing the emotional burden of repeated cycles in advanced maternal age. ⨠Whatâs new 𧪠Trial design and outcomes đ§ Why this matters after 35 đĽ Who may benefit most đ° Costs, access, and […]
⨠Whatâs New University of Florida scientists developed an experimental mRNA cancer vaccine that eliminated tumors in mouse models of melanoma, bone cancer, and brain cancer by activating broad typeâI interferonâdriven immunity rather than targeting specific tumor antigens. 𧪠How This Vaccine Differs đ Why It Matters 𧍠Key Preclinical Findings (Mice) đ Context and […]
đ°ď¸ Mission Overview A team led by Cedars-Sinai Medical Center is sending stem cells to the International Space Station to create the first heart and brain organoids grown in space. The launch is scheduled for 2:45 a.m. EDT Sunday on NASAâs 33rd commercial resupply mission. By leveraging microgravity, researchers aim to overcome Earth-bound limitations in […]
đ Whatâs New A team from Oxford Universityâs Department of Chemistry (McCullagh Group) has unveiled a metabolomics protocol that overcomes a decadesâold bottleneck: directly coupling anionâexchange chromatography (AEC) to mass spectrometry (MS). By integrating electrolytic ionâsuppression after chromatographic separation, the method enables sensitive detection of highly polar and ionic metabolites that drive primary cellular pathwaysâlong […]
Nature study shows cancer-induced nerve injury drives resistance to anti-PD-1 therapy; IL-6/IFN pathways emerge as actionable targets. đ§ Whatâs New A multi-institutional team led by Moffitt Cancer Center, Karolinska Institutet, and MD Anderson has uncovered a previously unknown mechanism by which cancers co-opt the nervous system to resist immunotherapy. Published today in Nature, the study […]
Baylor scientists map genes in adult brain stem cells, revealing targets for treating dementia, depression, and unexplained neurological disorders. ⨠Whatâs New Scientists at Baylor College of Medicine have mapped the genetic program of neural stem and progenitor cells responsible for generating new neurons in the adult brainâunlocking a roadmap for novel therapies in neurological […]
UPenn scientists show retrosplenial complex and superior parietal lobule form an internal compass, stabilizing facing direction during navigation. ⨠Whatâs New Researchers at the University of Pennsylvania have identified two brain regionsâthe retrosplenial complex (posterior-medial cortex) and the superior parietal lobuleâthat function as an internal neural compass, maintaining a stable sense of facing direction during […]
đ¨ Breaking News in Bladder Cancer Research The IMvigor011 trial marks a major breakthrough in muscle-invasive bladder cancer (MIBC) care. For the first time, researchers demonstrated that circulating tumor DNA (ctDNA) testing with Signatera can predict which patients truly benefit from adjuvant immunotherapy after surgery. This is a game-changer for oncology â reducing overtreatment and ensuring personalized, precise cancer care. đ Why IMvigor011 Matters for Bladder […]
How a Pregnancy Vaccine Is Revolutionizing RSV Protection for Newborns A major study from the UK has delivered groundbreaking news for parents: vaccinating mothers against respiratory syncytial virus (RSV) in late pregnancy leads to a striking 72% drop in newborn hospitalizations due to severe RSV infections. This new approach is poised to reshape the way […]
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